WANG Xinyan,ZHOU Tong,LI Jinglei,et al.Discussion on the Formation and Prevention Strategies of Chemotherapy Resistance of Malignant Tumor Based on “Yin Fire” Theory[J].Journal of Traditional Chinese Medicine,2023,64(20):2082-2085.
WANG Xinyan,ZHOU Tong,LI Jinglei,et al.Discussion on the Formation and Prevention Strategies of Chemotherapy Resistance of Malignant Tumor Based on “Yin Fire” Theory[J].Journal of Traditional Chinese Medicine,2023,64(20):2082-2085.DOI: 10.13288/j.11-2166/r.2023.20.007.
Discussion on the Formation and Prevention Strategies of Chemotherapy Resistance of Malignant Tumor Based on “Yin Fire” Theory
Chemotherapy is currently the main clinical treatment method for malignant tumors, and chemotherapy resistance is the main factor leading to chemotherapy failure and malignant tumor recurrence and metastasis. The cha-racteristics of malignant tumors formation were regarded as similar to the “
Yin
Fire” theory, manifested that deficiency of original
qi
as the foundation of malignant tumors, imbalance of original
qi
and
yin
fire as the internal cause of malignant tumor progression, and the internal environment of phlegm-blood stasis-toxicity-deficiency caused by
yin
fire promoted the formation of chemoresistance. In the treatment of chemoresistance of malignant tumors, traditional Chinese medicine should focus on treating disease before its onset by tonifying the spleen and strengthening the middle, nou-rishing the original
qi
, and reinforcing healthy
qi
and anti-cancer; during the treatment, the clinicians should regulate the
qi
and detoxify to clear
yin
fire, and improve the internal environment. Summarily, the strategies were adjusting the balance of internal environment of original
qi
and
yin
fire, and conducting a comprehensive treatment during the whole process, to provide new ideas for the treatment of chemoresistance of malignant tumors with traditional Chinese medicine.
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Keywords
references
LUO H , VONG CT , CHEN HB , et al . Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine [J]. Chinese Med , 2019 , 14 : 48 . doi: 10.1186/s13020-019-0270-9 http://dx.doi.org/10.1186/s13020-019-0270-9 .
PARAS F , SAURABH S , NAITIK J , et al . Tumor-promoting aftermath post-chemotherapy: a focus on breast cancer [J]. Life Sciences , 2022 , 310 : 121125 . doi: 10. 1016/j.lfs.2022.121125 http://dx.doi.org/10.1016/j.lfs.2022.121125 .
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