Integration of Traditional Chinese and Western Medicine in the Treatment of Liver Transplant Patient with Severe COVID-19： A Case Report

YAO Chensi; LI Xiuyang; LI Hui; XIE Weinan; BAO Tingting; ZHOU Danni; XIAO Mingzhong; JULAITI Abdulkeremu

doi:10.13288/j.11-2166/r.2023.23.014

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Integration of Traditional Chinese and Western Medicine in the Treatment of Liver Transplant Patient with Severe COVID-19： A Case Report

更新时间：2023-11-24

- Integration of Traditional Chinese and Western Medicine in the Treatment of Liver Transplant Patient with Severe COVID-19： A Case Report
  增强出版
- Journal of Traditional Chinese Medicine Vol. 64, Issue 23, Pages: 2457-2460(2023)
- 作者机构：
  
  1.浙江中医药大学附属第一医院/浙江省中医院，浙江省杭州市上城区邮电路54号，310003
  2.中国中医科学院广安门医院
  3.新疆医科大学附属中医医院
  4.北京中医药大学
  5.甘肃中医药大学
  6.湖北省中医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2023.23.014
  CLC：
- Received：27 March 2023，
  
  Revised：2023-07-13，
  
  Published：02 December 2023
- 稿件说明：
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姚晨思,李修洋,李慧等.中西医结合治疗肝移植患者合并新型冠状病毒感染（重型）1例[J].中医杂志,2023,64(23):2457-2460.

YAO Chensi,LI Xiuyang,LI Hui,et al.Integration of Traditional Chinese and Western Medicine in the Treatment of Liver Transplant Patient with Severe COVID-19： A Case Report[J].Journal of Traditional Chinese Medicine,2023,64(23):2457-2460.
姚晨思,李修洋,李慧等.中西医结合治疗肝移植患者合并新型冠状病毒感染（重型）1例[J].中医杂志,2023,64(23):2457-2460. DOI： 10.13288/j.11-2166/r.2023.23.014.

YAO Chensi,LI Xiuyang,LI Hui,et al.Integration of Traditional Chinese and Western Medicine in the Treatment of Liver Transplant Patient with Severe COVID-19： A Case Report[J].Journal of Traditional Chinese Medicine,2023,64(23):2457-2460. DOI： 10.13288/j.11-2166/r.2023.23.014.

摘要

肝移植患者术后需终身接受免疫疗法，若合并新型冠状病毒感染则患者机体免疫功能将面临双重打击。报告在“寒湿疫”辨治体系指导下采取中西医结合方法治疗肝移植合并重型新型冠状病毒肺炎患者1例，治疗方案为西医治疗采取抗病毒、免疫抑制等疗法，重在维持患者体内免疫平衡状态；中医治疗则在此基础上正确辨识患者所处的证候阶段，针对核心病机，运用宣畅气机、清热化湿、泻肺平喘等治法，治疗后患者临床症状及肝功能明显改善，且及时阻止了病情进一步发展并缩短了康复时间。

Abstract

Liver transplant patients require lifelong immunotherapy， and if they are infected by SARS-Cov-2， their immune function will face double whammy. This report described the integrated approach of traditional Chinese and western medicine in the treatment of a liver transplant patient with severe COVID-19. The treatment was involved with western medicine such as antiviral， immunosuppressive， focusing on maintaining immune balance. Traditional Chinese medicine was given based on the differentiation of syndromes， targeting at the core pathogenesis and using methods such as promoting

circulation， clearing heat and resolving dampness， draining lung and relieving panting. Following the treatment， the patient exhibited notable improvement in clinical symptoms and liver function， leading to the effective cessation of disease progression and a shortened recovery period.

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references

RABINOWICH L ， GRUPPER A ， BARUCH R ， et al . Low immunogenicity to SARS-CoV-2 vaccination among liver transplant recipients ［J］. J Hepatol ， 2021 ， 75 （ 2 ）： 435 - 438 .

WEBB GJ ， MARJOT T ， COOK JA ， et al . Outcomes following SARS-CoV-2 infection in liver transplant recipients： an international registry study ［J］. Lancet Gastroenterol Hepatol ， 2020 ， 5 （ 11 ）： 1008 - 1016 .

仝小林，李修洋，赵林华，等 . 从“寒湿疫”角度探讨新型冠状病毒肺炎的中医药防治策略［J］. 中医杂志， 2020 ， 61 （ 6 ）： 465 - 470，553 .

杨映映，李青伟，鲍婷婷，等 . 仝小林院士辨治新型冠状病毒肺炎：“寒湿疫”辨治体系的形成、创新与发展［J］. 世界中医药， 2022 ， 17 （ 6 ）： 833 - 837，842 .

鲍婷婷，杨映映，黄飞剑，等 . 论寒湿疫之瘀热入营［J］. 中医杂志， 2021 ， 61 （ 8 ）： 645 - 649 .

THULUVATH PJ ， ROBARTS P ， CHAUHAN M . Analysis of antibody responses after COVID-19 vaccination in liver transplant recipients and those with chronic liver diseases ［J］ Hepatol ， 2021 ， 75 （ 6 ）： 1434 - 1439 .

杨小玲，万娟，任秋平，等 . 新型冠状病毒感染肺炎疫情下肝移植受者住院及居家防控策略［J］. 中国普外基础与临床杂志， 2020 ， 27 （ 4 ）： 393 - 395 .

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