This article applied the five-viscera correlation theory proposed by Professor DENG Tietao to the field of gynecology， and combined with Professor LUO Yuankai's theory of female reproductive regulation axis of traditional Chinese medicine （TCM）， to identify from the perspective of the overall transmission of diseases between the five-viscera correlation theory， which affects the female reproductive regulation axis of TCM and leads to reproductive disorders. It advocates breaking away from specialized barriers， forming a new medical concept of holism， combining multiple specialties， and using the concept of treating diseases before they occur to prevent and treat reproductive disorders caused by chronic diseases in various departments； in the meanwhile， paying attention to female patients with chronic diseases in various specialties who have been using medication for a long period of time； making sure that they understand menstruation in adolescent and childbearing females， checking the function of the ovaries in a timely manner， and protecting their fertility； so as to propose new ideas of research on TCM theories， as well as providing a new concept for clinical research on integration of TCM with Western medicine.