Exploring the “Inflammation-Cancer” Transformation of Ulcerative Colitis and Its Prevention and Treatment Based on the Method of Regulating Qi and Resolving Toxins
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Exploring the “Inflammation-Cancer” Transformation of Ulcerative Colitis and Its Prevention and Treatment Based on the Method of Regulating Qi and Resolving Toxins
Journal of Traditional Chinese MedicineVol. 65, Issue 5, Pages: 469-473(2024)
YANG Bingwei,CHEN Xue,WANG Chenglei,et al.Exploring the “Inflammation-Cancer” Transformation of Ulcerative Colitis and Its Prevention and Treatment Based on the Method of Regulating Qi and Resolving Toxins[J].Journal of Traditional Chinese Medicine,2024,65(05):469-473.
YANG Bingwei,CHEN Xue,WANG Chenglei,et al.Exploring the “Inflammation-Cancer” Transformation of Ulcerative Colitis and Its Prevention and Treatment Based on the Method of Regulating Qi and Resolving Toxins[J].Journal of Traditional Chinese Medicine,2024,65(05):469-473.DOI: 10.13288/j.11-2166/r.2024.05.006.
Exploring the “Inflammation-Cancer” Transformation of Ulcerative Colitis and Its Prevention and Treatment Based on the Method of Regulating Qi and Resolving Toxins
and resolving toxins, this paper discussed the core pathogenesis of “inflammation-cancer” transformation of ulcerative colitis. It is believed that the disorder of
qi
movement, endogenous pathogenic factors of “heat, stasis and dampness” are cemented in the large intestine, and the pathogenic factors are too excessive to be solved, which will become toxic after a long time and lead to cancerous changes. Clinical prevention and treatment applies the method of regulating
qi
and resolving toxins, and the method of regulating
qi
was proposed as clearing internal
qi
, regulating blood
qi
and strengthening spleen
qi
, so as to clear heat, dissipate blood stasis and dissolve dampness; different methods of regulating
qi
and resolving toxins were flexibly combined according to the pathogenic characteristics of different stages of toxicity, in order to interrupt the process of “inflammation-cancer” transformation of ulcerative colitis.
VENKATARAMAN S , MOHAN V , RAMAKRISHNA BS , et al . Risk of colorectal cancer in ulcerative colitis in India [J]. J Gastroenterol Hepatol , 2005 , 20 ( 5 ): 705 - 709 .
ISHIBASHI N , HIROTA Y , IKEDA M , et al . Ulcerative colitis and colorectal cancer: a follow-up study in Fukuoka, Japan [J]. Int J Epidemiol , 1999 , 28 ( 4 ): 609 - 613 .
GRETEN FR , GRIVENNIKOV SI . Inflammation and cancer:triggers, mechanisms, and consequences [J]. Immunity , 2019 , 51 ( 1 ): 27 - 41 .
CAO H , LIU X , AN Y , et al . Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine [J]. Sci Rep , 2017 , 7 ( 1 ): 10322 .
JOHNSON AM , HARMSEN WS , ANIWAN S , et al . Prevalence and impact of obesity on disease-specific outcomes in a population-based cohort of patients with ulcerative colitis [J]. J Crohns Colitis , 2021 , 15 ( 11 ): 1816 - 1823 .
Comparative Study on the Effects of Qingchang Wenzhong Decoction (清肠温中方) on the Intestinal Mucus Barrier in Conventional and Pseudo-Germ-Free Model Mice of Acute Ulcerative Colitis
Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen
Characteristics of Traditional Chinese Medicine Syndromes and Treatment Rules in Ulcerative Colitis Patients in Jiangsu Province:Based on Real-World Data
Clinical Efficacy of Shenyu Guanchang Formula (参榆灌肠方) Enema Combined with Oral Mesalazine in the Treatment of Left-Sided Ulcerative Colitis with Large Intestine Damp-Heat Syndrome and Network Pharmacology Research
Traditional Chinese Medicine Therapy for Active Ulcerative Colitis:A Multicenter Bidirectional Cohort Study
Related Author
GAO Mingxu
LIU Leilei
LU Lijie
WANG Jiali
HU Juncong
LIN Yangzhe
LIU Qirui
DONG Yue
Related Institution
Dongfang Hospital,Beijing University of Chinese Medicine
School of Traditional Chinese Medicine,Beijing University of Chinese Medicine
Institute of Spleen and Stomach Diseases,Xiyuan Hospital,China Academy of Chinese Medical Sciences
Jiangsu Province Hospital of Chinese Medicine/Affiliated Hospital of Nanjing University of Chinese Medicine
Jiangsu Provincial Hospital of Chinese Medicine/Affiliated Hospital of Nanjing University of Chinese Medicine