QIN Yi'nan,YANG Lihong,BAI Yang,et al.Electroacupuncture Combined with Point Bloodletting and Cupping for Idiopathic Facial Palsy in Acute Stage of 40 Cases:A Randomized Controlled Trial[J].Journal of Traditional Chinese Medicine,2024,65(14):1458-1463.
QIN Yi'nan,YANG Lihong,BAI Yang,et al.Electroacupuncture Combined with Point Bloodletting and Cupping for Idiopathic Facial Palsy in Acute Stage of 40 Cases:A Randomized Controlled Trial[J].Journal of Traditional Chinese Medicine,2024,65(14):1458-1463.DOI: 10.13288/j.11-2166/r.2024.14.008.
Electroacupuncture Combined with Point Bloodletting and Cupping for Idiopathic Facial Palsy in Acute Stage of 40 Cases:A Randomized Controlled Trial
To explore the influence of electroacupuncture combined with point bloodletting and cupping for facial nerve function recovery in acute stage of idiopathic facial palsy (IFP).
Methods
2
Eighty patients with IFP in the acute stage were randomly divided into 40 cases each in the treatment group and the control group. In the control group, oral prednisone acetate tablets were administered during the acute stage when the disease duration was less than 10 days; and electroacupuncture and flash cupping were provided during the recovery stage when the disease duration was more than 10 days, five times a week. For treatment group in acute stage, the stellate ganglion, vagus nerve stimulation point in the auricular cavity, Yifeng (TE 17) and Tinghui (GB 2) were needled on the affected side on the basis of the treatment of control group, with Yifeng and Tinghui connecting to electroacupuncture apparatus, once a day; point bloodletting and then cupping in Yifeng 2 times a week; in recovery stage, the treatment was the same as that of the control group. Both groups were treated until the 45th day from onset. The primary outcome was the Toronto facial grading system (SFGS), and the secondary outcomes included house-brackmann (H-B) grade, facial disability index (FDI) score, and number of H-B grade-Ⅰ cases. Adverse events were recorded in both groups.
Results
2
The SFGS scores of the patients in both groups were higher on the 10th, 30th and 45th days after onset of disease compared with those before the treatment (
P
<0.05); the H-B grade was lower on the 30th and 45th days after the onset of the disease compared with those before the treatment (
P
<0.05); and the facial disability index physical function (FDIP) and facial disability index social function (FDIS) scores were higher on the 30th and 45th days after onset of disease (
P
<0.05). SFGS scores of patients in the treatment group were significantly higher than those of the control group on the 30th and 45th days after onset (
P
<0.05); H-B grade was significantly lower than that of the control group on the 30th and 45th days after onset (
P
<0.05); and FDIP scores on the 45th day after onset, and FDIS scores on the 30th and 45th days after onset were significantly higher than those of the control group (
P
<0.05). At the end of treatment, 77.50% (31 cases) achieved H-B grade-Ⅰ in the treatment group, which was more than 55.00% (22 cases) in the control group (
P
<0.05). No adverse events occurred in either group.
Conclusion
2
Electroacupuncture combined with point bloodletting and cupping for IFP in acute stage can improve the recovery degree of facial nerve function, improve effectiveness, and show a high degree of safety.
关键词
Keywords
references
MASTERSON L , VALLIS M , QUINLIVAN R , et al . Assessment and management of facial nerve palsy [J]. BMJ , 2015 , 351 : h3725 . doi: 10.1136/bmj.h3725 http://dx.doi.org/10.1136/bmj.h3725 .
YANAGIHARA N . Incidence of Bell's palsy [J]. Ann Otol Rhinol Laryngol Suppl , 1988 , 137 : 3 - 4 . doi: 10. 1177/00034894880976s301 http://dx.doi.org/10.1177/00034894880976s301 .
ALAM DS , HAFFEY T , VAKHARIA K , et al . Sternohyoid flap for facial reanimation: a comprehensive preclinical evaluation of a novel technique [J]. JAMA Facial Plast Surg , 2013 , 15 ( 4 ): 305 - 313 .
ZHAO JP , PIAO YZ , WANG J . Effect of acupuncture combined with blood-letting by a three-edged needle on 50 cases of Bell's palsy at the acute stage [J]. J Tradit Chin Med , 2010 , 30 ( 2 ): 118 - 121 .
SULLIVAN FM , SWAN IRC , DONNAN PT , et al . Early treatment with prednisolone or acyclovir in Bell's palsy [J]. N Engl J Med , 2007 , 357 ( 16 ): 1598 - 1607 .
KHEDR EM , BADRY R , ALI AM , et al . Steroid/antiviral for the treatment of Bell's palsy: double blind randomized clinical trial [J]. Restor Neurol Neurosci , 2016 , 34 ( 6 ): 897 - 905 .
ROSS BG , FRADET G , NEDZELSKI JM . Development of a sensitive clinical facial grading system [J]. Otolaryngol Head Neck Surg , 1996 , 114 ( 3 ): 380 - 386 .
谭冠先 . 疼痛诊疗学 [M]. 北京 : 人民卫生出版社 , 2001 : 31 .
HOUSE JW , BRACKMANN DE . Facial nerve grading system [J]. Otolaryngol Head Neck Surg , 1985 , 93 ( 2 ): 146 - 147 .
VANSWEARINGEN JM , BRACH JS . The facial disabi-lity index: reliability and validity of a disability assessment instrument for disorders of the facial neuromuscular system [J]. Phys Ther , 1996 , 76 ( 12 ): 1288 - 1298,1300 .
ROWLANDS S , HOOPER R , HUGHES R , et al . The epidemiology and treatment of Bell's palsy in the UK [J]. Eur J Neurol , 2002 , 9 ( 1 ): 63 - 67 .
ENGSTORM M , THUOMAS KA , NAESER P , et al . Facial nerve enhancement in Bell's palsy demonstrated by different gadolinium-enhanced magnetic resonance imaging techniques [J]. Arch Otolaryngol Head Neck Surg , 1993 , 119 ( 2 ): 221 - 225 .
KOZU H , TAMURA E , PARRY GJ . Endoneurial blood supply to peripheral nerves is not uniform [J]. J Neurol Sci , 1992 , 111 ( 2 ): 204 - 208 .
TIEN R , DILLON WP , JACKLER RK . Contrast-enhanced MR imaging of the facial nerve in 11 patients with Bell's palsy [J]. AJR Am J Roentgenol , 1990 , 155 ( 3 ): 573 - 579 .
MYCKATYN TM , MACKINNON SE . A review of facial nerve anatomy [J]. Semin Plast Surg , 2004 , 18 ( 1 ): 5 - 12 .
FUJIWARA T , HATO N , GYO K , et al . Prognostic factors of Bell's palsy: prospective patient collected observational study [J]. Eur Arch Otorhinolaryngol , 2014 , 271 ( 7 ): 1891 - 1895 .
BAUGH RF , BASURA GJ , ISHII LE , et al . Clinical practice guideline: Bell's palsy executive summary [J]. Otolaryngol Head Neck Surg , 2013 , 149 ( 5 ): 656 - 663 .
QIN YN , YANG LH , ZHANG M , et al . Efficacy evaluation and mechanism study of electroacupuncture intervention in acute phase of IFP:study protocol for a rando-mized controlled trial [J]. Trials , 2021 , 22 ( 1 ): 663 .
SITTEL C , STENNERT E . Prognostic value of electromyography in acute peripheral facial nerve palsy [J]. Otol Neurotol , 2001 , 22 ( 1 ): 100 - 104 .
DEVRIESE PP , SCHUMACHER T , SCHEIDE A , et al . Incidence, prognosis and recovery of Bell's palsy. A survey of about 1000 patients (1974-1983) [J]. Clin Otolaryngol Allied Sci , 1990 , 15 ( 1 ): 15 - 27 .
Effect of Electroacupuncture on Metabolism-Inflammation Network in Patients with Simple Obesity:A Randomized Controlled Trial
Neck Seven-Line Method Combined with Periauricular Acupuncture for 33 Patients with Sudden Hearing Loss in Non-Acute Stage: A Randomized Controlled Trial
Methodological Issues in the Design,Evaluation,and Reporting of Randomized Controlled Trials with "Pattern Dominating Disease"
Acupuncture Treatment for Severe Bell's Palsy and Its Impact on Serum GDNF and NGF:A Randomized Controlled Trial
Effect of Heat-sensitive Moxibustion on Quality of Life and Immune Function in Non-Small Cell Lung Cancer Patients with Qi Deficiency and Phlegm Stasis Syndrome Undergoing Chemotherapy:A Randomized Controlled Trial
Related Author
SHU Qi
PENG Qiumei
XU Zhihao
FANG Shanshan
SHAO Wenjing
CHENG Hongliang
HUANG Rilong
YU Qing
Related Institution
Anhui University of Chinese Medicine
The Second Affiliated Hospital of Anhui University of Chinese Medicine
The First Affiliated Hospital of Anhui University of Chinese Medicine
Anhui Provincial Key Laboratory of Meridian and Zang-Fu Organs Interrelationships
Institute of Xin'an Medicine and Modernization of Traditional Chinese Medicine,Institute of Health,Hefei Comprehensive National Science Center