The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression

LI Ziyan; LIU Xinzi; YIN Dongqing; ZHU Hong; JIA Hongxiao

doi:10.13288/j.11-2166/r.2024.14.009

您当前的位置：

首页 >

文章列表页 >

The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression

更新时间：2024-07-19

- The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression
- Journal of Traditional Chinese Medicine Vol. 65, Issue 14, Pages: 1464-1468(2024)
- 作者机构：
  
  1.首都医科大学附属北京安定医院，北京市西城区德胜门外安康胡同5号，100088
  2.首都医科大学/人脑保护高精尖创新中心
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2024.14.009
  CLC：
- Received：12 December 2023，
  
  Revised：2024-05-10，
  
  Published：17 July 2024
- 稿件说明：
移动端阅览
李自艳,刘鑫子,尹冬青等.基于复杂网络与线性回归分析双相情感障碍患者常见躯体症状与五态人格、情绪症状的相关性[J].中医杂志,2024,65(14):1464-1468.

LI Ziyan,LIU Xinzi,YIN Dongqing,et al.The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression[J].Journal of Traditional Chinese Medicine,2024,65(14):1464-1468.
李自艳,刘鑫子,尹冬青等.基于复杂网络与线性回归分析双相情感障碍患者常见躯体症状与五态人格、情绪症状的相关性[J].中医杂志,2024,65(14):1464-1468. DOI： 10.13288/j.11-2166/r.2024.14.009.

LI Ziyan,LIU Xinzi,YIN Dongqing,et al.The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression[J].Journal of Traditional Chinese Medicine,2024,65(14):1464-1468. DOI： 10.13288/j.11-2166/r.2024.14.009.

摘要

目的

分析双相情感障碍（BD）患者躯体症状、五态人格、情绪症状之间的关系，为BD的临床诊疗提供参考。

方法

收集纳入BD患者的基本信息，采用自制躯体症状调查表调查出现频次＞20%的躯体症状，将其得分作为躯体症状评分，采用24 项汉密尔顿抑郁量表（HAMD）评价患者抑郁症状，杨氏躁狂量表（YMRS）评价患者躁狂症状，汉密尔顿焦虑量表（HAMA）评价患者焦虑症状，五态人格测验量表评价患者五态人格，包括太阳人格、少阳人格、阴阳和平人格、少阴人格、太阴人格得分。采用复杂网络分析和线性回归模型分析躯体症状得分与五态人格得分、HAMD评分、YMRS评分、HAMA评分的相关性。

结果

纳入BD患者269例，出现频次＞20%的躯体症状有19个，前3位是乏力（152例，56.51%）、口舌干燥（137例，50.93%）、喜冷饮（112例，41.64%），躯体症状评分为［7.0（0，10.0）］分；YMRS评分为［3.0（0，7.5）］分；HAMD评分为［11.0（5.0，18.0）］分；HAMA评分为［6.0（2.0，10.0）］分。五态人格中，太阳人格［10.0（7.0，13.0）］分；少阳人格［10.0（7.5，13.0）］分；阴阳平和人格［5.0（3.0，7.0）］分；少阴人格［13.0（10.0，16.0）］分；太阴人格［14.0（9.0，18.0）］分。复杂网络分析结果显示，BD患者躯体症状与太阴人格得分（

=0.23）、HAMD评分（

=0.21）、YMRS评分（

=0.13）呈正相关；太阴人格得分与HAMD评分呈正相关（

=0.17），与YMRS评分呈负相关（

=-0.03）。线性回归模型分析结果显示，躯体症状得分与HAMD评分（

=0.138，

=0.003）、YMRS评分（

=0.128，

=0.006）、太阴人格得分（

=0.182，

＜0.001）呈正相关。

结论

抑郁、躁狂、太阴人格是BD患者躯体症状的独立风险因素，五态人格中太阴人格与BD患者的躯体症状关系密切。

Abstract

Objective

To analyze the relationship between somatic symptoms， five-state personality and emotional symptoms of bipolar disorder （BD）， and to provide a reference for the clinical diagnosis and treatment of BD.

Methods

The basic information of the BD patients was collected， and the self-administered somatic symptom questionnaire was used to investigate the somatic symptoms with a frequency of ＞20%， which were scored as the somatic symptom scores； the 24-item Hamilton Depression Scale （HAMD） was used to evaluate the patients' depressive symptoms， the Young Mania Rating Scale （YMRS） was used to evaluate the patients' manic symptoms， the Hamilton Anxiety Scale （HAMA） was used to evaluate the patients' anxiety symptoms， and Five-State Personality Test was used to evaluate the patients' five-state personality （including

taiyang

personality，

shaoyang

personality，

yin

yang

balance personality，

shaoyin

personality， and

taiyin

personality）. Network analysis and linear regression were used to analyse the correlation between the somatic symptom scores and the five-state personality scores， HAMD scores， YMRS scores， and HAMA scores.

Results

There were 269 patients with BD included， and 19 somatic symptoms with a frequency of ＞20%， the top three being lack of strength （152 cases， 56.51%）， dry mouth （137 cases， 50.93%）， and preference for cold drinks （112 cases， 41.64%）， and the somatic symptom scores were ［7.0 （0，10.0）］ points； the YMRS scores were ［3.0 （0， 7.5）］ points； the HAMD scores were ［11.0 （5.0， 18.0）］ points； and HAMA score was ［6.0 （2.0， 10.0）］ points. Among the five-state personalities，

taiyang

personality ［10.0 （7.0， 13.0）］ score；

shaoyang

personality ［10.0 （7.5， 13.0）］ score；

yin

yang

balance personality ［5.0 （3.0， 7.0）］ score；

shaoyin

personality ［13.0 （10.0， 16.0）］ score； and

taiyin

personality ［14.0 （9.0， 18.0）］ score. Complex network analysis showed that BD somatic symptoms were positively correlated with

taiyin

personality score （

= 0.23）， HAMD score （

= 0.21）， and YMRS score （

= 0.13）；

taiyin

personality score was positively correlated with HAMD score （

= 0.17） and negatively correlated with YMRS score （

= -0.03）. Linear regression analyses showed that somatic symptom scores were positively correlated with HAMD score （

= 0.138，

= 0.003）， YMRS score （

= 0.128，

= 0.006）， and

taiyin

personality scores （

= 0.182，

＜0.001）.

Conclusion

Depression， mania， and

taiyin

personality are independent risk factors for somatic symptoms in patients with BD， and

taiyin

personality is strongly associated with somatic symptoms in patients with BD.

关键词

Keywords

references

STUBBS B ， VANCAMPFORT D ， SOLMI M ， et al . How common is bipolar disorder in general primary care attendees？ A systematic review and meta-analysis investigating prevalence determined according to structured clinical assessments ［J］. Aust N Z J Psychiatry ， 2016 ， 50 （ 7 ）： 631 - 639 .

美国精神医学学会 . 精神障碍诊断与统计手册［M］. 5版 . 张道龙，译. 北京：北京大学出版社， 2015 .

EDGCOMB JB ， TSENG CH ， KERNER B . Medically unexplained somatic symptoms and bipolar spectrum disorders： a systematic review and meta-analysis ［J］. J Affect Disord ， 2016 ， 204 ： 205 - 213 . doi： 10.1016/j.jad. 2016. 06.029 http://dx.doi.org/10.1016/j.jad.2016.06.029 .

STUBBS B ， EGGERMONT L ， MITCHELL AJ ， et al . The prevalence of pain in bipolar disorder： a systematic review and large-scale meta-analysis ［J］. Acta Psychiatr Scand ， 2015 ， 131 （ 2 ）： 75 - 88 .

ARNOLD LM ， WITZEMAN KA ， SWANK ML ， et al . Health-related quality of life using the SF-36 in patients with bipolar disorder compared with patients with chronic back pain and the general population ［J］. J Affect Disord ， 2000 ， 57 （ 1/3 ）： 235 - 239 .

YATHAM LN ， LECRUBIER Y ， FIEVE RR ， et al . Quality of life in patients with bipolar I depression： data from 920 patients ［J］. Bipolar Disord ， 2004 ， 6 （ 5 ）： 379 - 385 .

BARNETT JH ， HUANG J ， PERLIS RH ， et al . Personality and bipolar disorder： dissecting state and trait associations between mood and personality ［J］. Psychol Med ， 2010 ， 41 （ 8 ）： 1593 - 1604 .

SANTESTEBAN-ECHARRI O ， MACQUEEN G ， GOLDSTEIN BI ， et al . Personality and risk for serious mental illness ［J］. Early Interv Psychiatry ， 2021 ， 15 （ 1 ）： 133 - 139 .

杨秋莉，薛崇成 . 中医学心理学的个性学说与五态人格测验［J］. 中国中医基础医学杂志， 2006 ， 12 （ 10 ）： 777 - 779 .

刘鑫子，李自艳，郑思思，等 . 基于聚类分析及贝叶斯网络的双相情感障碍抑郁发作中医证候的横断面研究［J］. 中医杂志， 2024 ， 65 （ 1 ）： 79 - 85 .

尹冬青，贾竑晓 . 双相情感障碍中医证候辨证分型标准专家共识［J］. 现代中医临床， 2021 ， 28 （ 6 ）： 1 - 8 .

朱虹，尹冬青，李自艳，等 . 双相情感障碍中医证素特点的初步探索［J］. 现代中医临床， 2019 ， 26 （ 4 ）： 29 - 33 .

张明园，何燕玲 . 精神科评定量表手册［M］. 长沙：湖南科学技术出版社， 2015 .

李黎，王昊，杜渐，等 . 五态人格测验的应用情况研究［J］. 世界中医药， 2015 ， 10 （ 5 ）： 801 - 804 .

蔡玉清，董书阳，袁帅，等 . 变量间的网络分析模型及其应用［J］. 心理科学进展， 2020 ， 28 （ 1 ）： 1781 - 1795 .

LÖVDAHL H ， BØEN E ， MALT EA ， et al . Somatic and cognitive symptoms as indicators of potential endophenotypes in bipolar spectrum disorders： an exploratory and proof-of-concept study comparing bipolar Ⅱ disorder with recurrent brief depression and healthy controls ［J］. J Affect Disord ， 2014 ， 166 ： 59 - 70 . doi： 10.1016/j.jad. 2014.04.056 http://dx.doi.org/10.1016/j.jad.2014.04.056 .

王琦 . 形神一体的形神观［J］. 中华中医药杂志， 2012 ， 27 （ 3 ）： 652 - 654 .

李自艳，刘鑫子，杜渐，等 . 双相情感障碍的中医五态人格特征初探［J］. 首都医科大学学报， 2021 ， 42 （ 3 ）： 408 - 411 .

王克勤，杨秋莉 . 中医心理学基础理论［M］. 北京：人民卫生出版社， 2013 ： 167 - 173 .

李黎，杜渐，王昊，等 . 中医五态人格的五行配属关系探讨［J］. 世界中医药， 2014 ， 9 （ 7 ）： 871 - 873 .

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Differentiation and Treatment of Bipolar Disorder based on Qi， Phlegm， Fire and Deficiency

Treatment of Adolescent Bipolar Disorder Based on the Opening-Closing-Pivot Theory

WANG Xixing's Experience in Differentiation and Treatment of Advanced Breast Cancer with Anxiety and Depression：Based on Shaoyang Pivot Theory

Differentiation and Treatment of Bipolar Disorder from the Relationship Between "Liver is Yin in Form and Yang in Function" and Bile Acid Metabolism

Traditional Chinese Medicine External Treatment Strategies for Somatic Symptoms of Depression：from the Perspective of the Five Body Constituents

Related Author

YU Yunfeng

HU Gang

ZHOU Manli

LUO Xiaoxin

ZHOU Xiahui

JIAN Weixiong

YUAN Zhaokai

LI Xiang

Related Institution

College of Chinese Medicine， Hunan University of Chinese Medicine

The First Affiliated Hospital of Hunan University of Chinese Medicine

The Third Affiliated Hospital of Beijing University of Chinese Medicine

The Third Clinical Medical College，Beijing University of Chinese Medicine

The First Clinical College，Shanxi University of Chinese Medicine

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰