FANG Dingya's Experience in Staged Treatment of Sjögren's Syndrome based on Dryness Toxin Theory

ZHANG Haoyu; HAN Shuhua; DONG Fei; DU Liyan; WANG Xin; ZHOU Caiyun; TANG Jinyang

doi:10.13288/j.11-2166/r.2024.15.005

您当前的位置：

首页 >

文章列表页 >

FANG Dingya's Experience in Staged Treatment of Sjögren's Syndrome based on Dryness Toxin Theory

更新时间：2024-08-01

- FANG Dingya's Experience in Staged Treatment of Sjögren's Syndrome based on Dryness Toxin Theory
- Journal of Traditional Chinese Medicine Vol. 65, Issue 15, Pages: 1550-1554(2024)
- 作者机构：
  
  1.中国中医科学院西苑医院，北京市海淀区西苑操场1号，100091
  2.中国中医科学院研究生院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2024.15.005
  CLC：
- Received：27 January 2024，
  
  Revised：2024-05-01，
  
  Published：02 August 2024
- 稿件说明：
移动端阅览
张皓瑜,韩淑花,董菲等.房定亚从燥毒分阶段论治干燥综合征经验[J].中医杂志,2024,65(15):1550-1554.

ZHANG Haoyu,HAN Shuhua,DONG Fei,et al.FANG Dingya's Experience in Staged Treatment of Sjögren's Syndrome based on Dryness Toxin Theory[J].Journal of Traditional Chinese Medicine,2024,65(15):1550-1554.
张皓瑜,韩淑花,董菲等.房定亚从燥毒分阶段论治干燥综合征经验[J].中医杂志,2024,65(15):1550-1554. DOI： 10.13288/j.11-2166/r.2024.15.005.

ZHANG Haoyu,HAN Shuhua,DONG Fei,et al.FANG Dingya's Experience in Staged Treatment of Sjögren's Syndrome based on Dryness Toxin Theory[J].Journal of Traditional Chinese Medicine,2024,65(15):1550-1554. DOI： 10.13288/j.11-2166/r.2024.15.005.

摘要

总结房定亚教授从燥毒分阶段论治干燥综合征的临证经验。认为干燥综合征病因为外感燥邪、耗伤精津，先后天不足、精衰血少，核心病机为燥毒内蕴，并从“燥金气化”的角度将其分为燥毒兼火热、燥毒兼湿热、燥毒兼痰瘀三个阶段论治。具体治疗强调主以祛邪，辅以滋阴清润之品，分阶段辨证论治，其中燥毒兼火热治当润燥解毒降火，方以自拟润燥解毒汤加减；燥毒兼湿热治当养阴清热利湿，方以春泽汤加减；燥毒兼痰瘀治当通络消痰散瘀，方以自拟散瘀消痰汤加减。

Abstract

This paper summarized the experience of Professor FANG Dingya in staged treatment of Sjögren's syndrome from the perspective of dryness toxin. It is believed that the cause of Sjögren's syndrome is externally-contracted dryness， consumption of essence and fluid， congenital and acquired essence deficiency， depleted essence and insu

fficient blood， and the core mechanism is internal accumulation of dryness toxin. The treatment can be divided into three stages， that is dryness toxin transforming into fire-heat， damp-heat and phlegm-stasis， from the perspective of dryness metal

transformation. It is emphasized to dispel pathogen mainly， to clear and moisten with

yin

-nourishing medicinals in supplementation， and to treat by stages based on syndrome differentiation. For dryness toxin with fire-heat， it is suggested to moisten dryness， resolve toxins and subdue fire， with self-made

Runzao Jiedu Decoction

（润燥解毒汤） in modification. For dryness toxin with damp-heat， the method of nourishing

yin

， clearing heat and draining dampness should be used， and

Chunze Decoction

（春泽汤） in modification is suggested. For dryness toxin with phlegm-stasis， it is recommended to unblock collaterals， disperse phlegm and dissipate stasis， with self-made

Sanyu Xiaotan Decoction

（散瘀消痰汤） in modification.

关键词

Keywords

references

中国医师协会风湿免疫科医师分会干燥综合征学组 . 原发性干燥综合征诊疗规范［J］. 中华内科杂志， 2023 ， 62 （ 9 ）： 1059 - 1067 .

FLORES-CHÁVEZ A ， KOSTOV B ， SOLANS R ， et al . Severe，life-threatening phenotype of primary Sjögren's syndrome：clinical characterisation and outcomes in 1580 patients （GEAS-SS Registry）［J］. Clin Exp Rheumatol ， 2018 ，36 Suppl 112 （ 3 ）： 121 - 129 .

王倩，戴生明 . 《2019年欧洲抗风湿病联盟干燥综合征局部与系统性治疗推荐》解读［J］. 中华临床免疫和变态反应杂志， 2020 ， 14 （ 3 ）： 179 - 182 .

PONTICELLI C ， GLASSOCK RJ . Prevention of complications from use of conventional immunosuppressants ：a critical review ［J］. J Nephrol ， 2019 ， 32 （ 6 ）： 851 - 870 .

中华中医药学会风湿病分会 . 干燥综合征病证结合诊疗指南［J］. 中医杂志， 2024 ， 65 （ 4 ）： 434 - 444 .

郭丽，李志军 . 感染与干燥综合征关系的研究进展［J］. 医学综述， 2017 ， 23 （ 8 ）： 1633 - 1637 .

MASLINSKA M . The role of Epstein-Barr virus infection in primary Sjögren′s syndrome ［J］. Curr Opin Rheumatol ， 2019 ， 31 （ 5 ）： 475 - 483 .

刘康丽，孙升云 . 先天之本与基因遗传相关性探析［J］. 陕西中医， 2010 ， 31 （ 12 ）： 1693 - 1695 .

ORTÍZ-FERNÁNDEZ L ， MARTÍN J ， ALARCÓN-RIQUELME ME . A summary on the genetics of systemic lupus erythematosus， rheumatoid arthritis， systemic sclerosis， and Sjögren's syndrome ［J］. Clin Rev Allergy Immunol ， 2023 ， 64 （ 3 ）： 392 - 411 .

BRITO-ZERON P ， ACAR-DENIZLI N ， ZEHER M ， et al . Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients： a cross-sectional study from the Big Data Sjögren Project Consortium ［J］. Ann Rheum Dis ， 2017 ， 76 （ 6 ）： 1042 - 1050 .

张欢，刘春红，吴斌 . 原发性干燥综合征的流行病学研究进展［J］. 现代预防医学， 2020 ， 47 （ 16 ）： 3056 - 3058，3063 .

罗成，叶远航，柯佳 . 从“壮火食气”探讨炎症对肺癌的影响［J］. 中医学报， 2024 ， 39 （ 4 ）： 689 - 694 .

莫小英，阮威君，郑锋玲，等 . 基于“气化则湿亦化”论治湿滞三焦［J］. 广州中医药大学学报， 2024 ， 41 （ 4 ）： 1048 - 1052 .

周靖惟，张星，李莎，等 . 基于“入血成分-复方功效-靶点通路”的四妙勇安汤潜在质量标志物研究［J］. 中草药， 2022 ， 53 （ 24 ）： 7795 - 7807 .

漆文霞，王钢，闫彦峰，等 . 基于中医瘀血理论探讨干燥综合征的发病机制及治疗［J］. 世界科学技术-中医药现代化， 2022 ， 24 （ 11 ）： 4279 - 4285 .

武少茹 . 夏枯草不同部位化学成分及活性研究［D］. 北京：中国中医科学院， 2023 .

李曼，张露蓉，金顺琪，等 . 白花蛇舌草不同提取液抗炎镇痛效应及化学成分比较研究［J］. 辽宁中医药大学学报， 2022 ， 24 （ 8 ）： 19 - 23 .

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

FANG Dingya's Experience in Staged Differentiation and Treatment of Connective Tissue Disease with Immune Thrombocytopenia Based on the Theory of Collateral Disease

Experience of LU Zhizheng in Treatment of Sjögren's Syndrome：from the view of Yin-Fire

Professor FANG Dingya′s Experience in Staged Treatment of Behcet′s Syndrome Uveitis based on the Theory of Collateral Disease

Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory

YANG Zhen's Interpretation of the Wumei Pill （乌梅丸） Based on the Theory of Qi Dynamics of Ministerial Fire

Related Author

LI Zhuanzhuan

TANG Jinyang

WANG Xin

DONG Fei

ZHOU Caiyun

YE Yuqing

FAN Bingbing

MA Fang

Related Institution

Tianjin University of Traditional Chinese Medicine

Xiyuan Hospital，China Academy of Chinese Medical Sciences

Guang'anmen Hospital， China Academy of Chinese Medical Sciences

Chinese Journal of Integrated Traditional And Western Medicine

The Second Clinical Medical College，Henan University of Chinese Medicine

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰