Based on the theory of "disease involving both dryness and dampness"， it is believed that the complex of dryness and dampness and the mutual stalemate between them produce the disease， forming a pathological state of dampness within dryness and dryness within dampness. The two can occur accompanied by each other， transform into each other， and coexist as a disease. According to the clinical characteristics of sjögren's syndrome-related dry eye disease （SS-DED）， it is believed that its symptoms can reflect the pathologi

cal state of coexistence of dryness and dampness， and that "disease involving both dryness and dampness" is the key pathogenesis. The main treatment principles are performing both purgation and tonification， and treating the dryness and dampness simultaneously. The treatment should focus on rectifying

qi

， fortifying spleen and dispelling dampness， as well as opening orifices， nou-rishing

yin

and moistening dryness， usually with

Shashen Maidong Decoction

（沙参麦冬汤） and

Xiangsha Liujunzi Decoction （

香砂六君子汤） in modifications. The theory of "disease involving both dryness and dampness" is expected to provide ideas for the diagnosis and treatment of SS-DED.