Differentiation and Treatment of Interstitial Cystitis/Bladder Pain Syndrome Based on the Theory of Sores and Ulcers

LIU Qiongqiong; PANG Ran; CHEN Yueying; TANG Junfeng; CAO Fengqin; MA Diyuan

doi:10.13288/j.11-2166/r.2024.16.014

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Differentiation and Treatment of Interstitial Cystitis/Bladder Pain Syndrome Based on the Theory of Sores and Ulcers

更新时间：2024-08-12

- Differentiation and Treatment of Interstitial Cystitis/Bladder Pain Syndrome Based on the Theory of Sores and Ulcers
- Journal of Traditional Chinese Medicine Vol. 65, Issue 16, Pages: 1712-1716(2024)
- 作者机构：
  
  1.北京中医药大学，北京市朝阳区北三环东路11号，100029
  2.中国中医科学院广安门医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2024.16.014
  CLC：
- Received：22 January 2024，
  
  Revised：2024-05-30，
  
  Published：17 August 2024
- 稿件说明：
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刘琼琼,庞然,陈月莹等.基于疮疡理论辨治间质性膀胱炎/膀胱疼痛综合征[J].中医杂志,2024,65(16):1712-1716.

LIU Qiongqiong,PANG Ran,CHEN Yueying,et al.Differentiation and Treatment of Interstitial Cystitis/Bladder Pain Syndrome Based on the Theory of Sores and Ulcers[J].Journal of Traditional Chinese Medicine,2024,65(16):1712-1716.
刘琼琼,庞然,陈月莹等.基于疮疡理论辨治间质性膀胱炎/膀胱疼痛综合征[J].中医杂志,2024,65(16):1712-1716. DOI： 10.13288/j.11-2166/r.2024.16.014.

LIU Qiongqiong,PANG Ran,CHEN Yueying,et al.Differentiation and Treatment of Interstitial Cystitis/Bladder Pain Syndrome Based on the Theory of Sores and Ulcers[J].Journal of Traditional Chinese Medicine,2024,65(16):1712-1716. DOI： 10.13288/j.11-2166/r.2024.16.014.

摘要

认为间质性膀胱炎/膀胱疼痛综合征（IC/BPS）内镜下广泛出血、Hunner溃疡等表现以及其病情反复、迁延难愈的特点与中医学疮疡的特征相符，治疗上可参考疮疡的中医治疗思路。IC/BPS病机多表现为本虚标实，以脾肾亏虚为本，湿热、瘀血为标。治疗以托、补之法为本，兼用消法，以活血清热、通络止痛治其标。临证常用内托生肌散加减以益气活血，消肿托毒；同时结合具体症状配合四君子汤或缩泉丸健脾补肾以扶正，并根据瘀血、湿热等兼证针对性配伍三棱、莪术等活血化瘀，薏苡仁、泽泻等清热利湿。

Abstract

It is believed that the endoscopic manifestations of interstitial cystitis/bladder pain syndrome （IC/BPS） such as extensive bleeding and Hunner's ulcers as well as its recurrent and prolonged condition are in line with the characteristics of sores and ulcers in traditional Chinese medicine （TCM）， and the treatment can be referred to TCM theory of sores and ulcers. The mechanism of IC/BPS is c

haracterized by root deficiency and branch excess. The root cause is deficiency of the spleen and kidney

， while the manifesting factors are dampness-heat and blood stasis. The treatment is based on the principles of promoting and supplementing， combining with resolving therapy， so that the symptoms could be relieved by promoting blood circulation and clearing heat， unblocking the collaterals and relieve pain. In clinical practice， modified

Neituo Shengji Powder

（内托生肌散） was commonly used to boost

and invigorate blood， expel swollen sore and express toxin； combining with

Sijunzi Decoction

（四君子汤） or

Suoquan Pill

（缩泉丸） based on specific symptoms to strengthen the spleen and kidneys， thereby reinforcing healthy

； according to concurrent symptoms like blood stasis， dampness heat， prescription with Sanleng （

Cyperus rotundus

）， Ezhu （

Curcuma aromatica Salisb

） to invigorate blood and dissolve stasis， or Yiyiren （

Coix lacryma

jobi

）， Zexie （

Alisma plantago

aquatica

） to clear heat and drain dampness.

关键词

Keywords

references

HANNO P . Diagnosis and treatment of interstitial cystitis/bladder pain syndrome ［J］. J Urol ， 2022 ， 208 （ 6 ）： 1178 .

CLEMENS JQ ， ERICKSON DR ， VARELA NP ， et al . Diagnosis and treatment of interstitial cystitis/bladder pain syndrome ［J］. J Urol ， 2022 ， 208 （ 1 ）： 34 - 42 .

DRISCOLL A ， TEICHMAN JM . How do patients with interstitial cystitis present？［J］. J Urol ， 2001 ， 166 （ 6 ）： 2118 - 2120 .

MCKERNAN LC ， WALSH CG ， REYNOLDS WS ， et al . Psychosocial co-morbidities in interstitial cystitis/bladder pain syndrome （IC/BPS）： a systematic review ［J］. Neurourol Urodyn ， 2018 ， 37 （ 3 ）： 926 - 941 .

CHEN A ， SHAHIYAN RH ， ANGER JT . Interstitial cystitis/bladder pain syndrome treatment： a systematic review of sexual health outcomes ［J］. Sex Med Rev ， 2022 ， 10 （ 1 ）： 71 - 76 .

谭仔龙，沈建武 . 中医药治疗间质性膀胱炎临床研究进展［J］. 中国医药导报， 2023 ， 20 （ 27 ）： 55 - 58 .

常炳龙，何莹，刘凯文，等 . 田德禄教授“内疡”理论治疗溃疡性结肠炎经验及用药规律［J］. 中国临床医生杂志， 2019 ， 47 （ 11 ）： 1375 - 1377 .

中国中西医结合学会泌尿外科专业委员会，湖北省中西医结合泌尿外科专业委员会 . 中西医结合诊疗间质性膀胱炎专家共识［J］. 中国中西医结合外科杂志， 2022 ， 28 （ 6 ）： 757 - 762 .

CHEN L ， DENG H ， CUI H ， et al . Inflammatory responses and inflammation-associated diseases in organs ［J］. Oncotarget ， 2017 ， 9 （ 6 ）： 7204 - 7218 .

NATHAN C ， DING A . Nonresolving inflammation ［J］. Cell ， 2010 ， 140 （ 6 ）： 871 - 882 .

HOMMA Y ， AKIYAMA Y ， TOMOE H ， et al . Clinical guidelines for interstitial cystitis/bladder pain syndrome ［J］. Int J Urol ， 2020 ， 27 （ 7 ）： 578 - 589 .

赵宜真 . 秘传外科方［M］. 北京：人民卫生出版社， 1991 ： 123 .

陈红风 . 中医外科学［M］. 2版 . 上海：上海科学技术出版社， 2021 ： 13 .

徐利，葛琼翔，林国强 . 基于“护场”理论探讨清热化瘀法促进肛肠术后感染切口愈合的机制［J］. 中成药， 2017 ， 39 （ 5 ）： 1106 - 1108 .

WHITMORE KE ， FALL M ， SENGIKU A ， et al . Hunner lesion versus non-Hunner lesion interstitial cystitis/bladder pain syndrome ［J］. Int J Urol ， 2019 ， 26 （ Suppl 1 ）： 26 - 34 .

AKIYAMA Y ， NIIMI A ， NOMIYA A ， et al . Efficacy and safety of intravesical dimethyl sulfoxide treatment for patients with refractory Hunner-type interstitial cystitis： real-world data postofficial approval in Japan ［J］. Int J Urol ， 2024 ， 31 （ 2 ）： 111 - 118 .

FALL M ， NORDLING J ， CERVIGNI M ， et al . Hunner lesion disease differs in diagnosis， treatment and outcome from bladder pain syndrome： an ESSIC working group report ［J］. Scand J Urol ， 2020 ， 54 （ 2 ）： 91 - 98 .

CARDOZO L ， ROVNER E ， WAGG A ， et al . Incontinence ［M］. 7th Edition . Bristol UK ： International Continence Society ， 2023 ： 1861 .

原景，杜韩，万梅绪，等 . 丹参有效成分及丹参类制剂抗炎药理作用的研究进展［J］. 药物评价研究， 2021 ， 44 （ 11 ）： 2322 - 2332 .

陈楚敏，谢佳芯，冼丽柠，等 . 治疗疮疡成方制剂的挖掘与分析［J］. 西部中医药， 2021 ， 34 （ 9 ）： 77 - 81 .

马青，赵明 . 《中医方剂大辞典》含全蝎-蜈蚣药对的方剂用药规律分析［J］. 中医药导报， 2020 ， 26 （ 13 ）： 106 - 109，113 .

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