Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment

ZHANG Yi; XIE Zhijun; HUANG Lin; WANG Qiao; LI Haichang; WEN Chengping

doi:10.13288/j.11-2166/r.2024.16.016

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Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment

更新时间：2024-08-12

- Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment
- Journal of Traditional Chinese Medicine Vol. 65, Issue 16, Pages: 1721-1724(2024)
- 作者机构：
  
  浙江中医药大学，浙江省杭州市滨江区滨文路548号，310053
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2024.16.016
  CLC：
- Received：06 January 2024，
  
  Revised：2024-05-30，
  
  Published：17 August 2024
- 稿件说明：
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张祎,谢志军,黄琳等.系统性红斑狼疮的伏毒病机演变及辨治[J].中医杂志,2024,65(16):1721-1724.

ZHANG Yi,XIE Zhijun,HUANG Lin,et al.Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2024,65(16):1721-1724.
张祎,谢志军,黄琳等.系统性红斑狼疮的伏毒病机演变及辨治[J].中医杂志,2024,65(16):1721-1724. DOI： 10.13288/j.11-2166/r.2024.16.016.

ZHANG Yi,XIE Zhijun,HUANG Lin,et al.Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2024,65(16):1721-1724. DOI： 10.13288/j.11-2166/r.2024.16.016.

摘要

提出系统性红斑狼疮（SLE）的病机演变可以概括为四个阶段：邪伏初期，病机潜伏；伏毒积聚，病情渐显；邪毒致损，病势凶猛；因损致虚，病程迁延。根据伏毒病机演变过程对SLE进行辨治：邪伏阶段表现为伏湿郁热，方用三仁汤加减；毒发阶段表现为热毒炽盛，方用犀角地黄汤合清瘟败毒饮加减；毒损阶段表现为毒损脏腑，方用青蒿鳖甲汤加减；正虚阶段表现为气血阴阳俱虚，方用燮理十全膏加减。

Abstract

It is proposed that the disease mechanism evolution of systemic lupus erythematosus can be summarized into four stages： initial invasion and latency， the pathogenesis remains concealing； latent toxin accumulation， the disease gradually becomes apparent； active toxin begins damaging， the disease manifests aggressively； damage resulting to deficiency， the disease course prolonged. Based on the stages of latent toxin evolution， the syndrome differentiation and treatment of systemic lupus erythematosus can be summarized as follows： during the initial latent stage， characterized by latent dampness and heat stagnation， modified

Sanren Decoction

（三仁汤） should be used； in the toxin outbreak stage， marked by intense heat toxin， modified

Xijiao Dihuang Decoction

（犀角地黄汤） combined with modified

Qingwen Baidu Decoction

（清瘟败毒饮） should be used； during the toxin damage stage， which presents as latent toxin damaging

zang

organs， modified

Qinghao Biejia Decoction

（青蒿鳖甲汤） should be used； in the healthy

deficiency stage， characteriz

ed by deficiencies of

， blood，

yin

， and

yang

， modified

Xieli Shiquan Ointment

（燮理十全膏） should be used.

关键词

Keywords

references

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Heilongjiang University of Chinese Medicine

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