CAO Boning,WANG Yaoxian.Application of Huangqi (Radix Astragali) in the Treatment of Membranous Nephropathy[J].Journal of Traditional Chinese Medicine,2024,65(16):1725-1729.
CAO Boning,WANG Yaoxian.Application of Huangqi (Radix Astragali) in the Treatment of Membranous Nephropathy[J].Journal of Traditional Chinese Medicine,2024,65(16):1725-1729.DOI: 10.13288/j.11-2166/r.2024.16.017.
Application of Huangqi (Radix Astragali) in the Treatment of Membranous Nephropathy
The core pathogenesis of membranous nephropathy is spleen-kidney depletion and dampness-stasis blocking collaterals, in which spleen-kidney depletion runs through the whole process of membranous nephropathy. Spleen and kidney depletion often occurs in the early stage of membranous nephropathy, accompanied by the progression of the disease and the stagnation of deficiency and
qi
, which leads to the obstruction of kidney collaterals by patho-logical products such as phlegm, blood stasis and water-dampness, and then the formation of stasis obstruction in kidney collaterals over time. Huangqi (
Radix Astragali
) as an important herb for supplementing spleen and boosting kidney can be used to fortify spleen, consolidate kidney and generate essence, and to boost
qi
, expel blood and unblock collaterals when treating membranous nephropathy. With combined medicinals, it can dispel and remove wind, astringe, store and consolidate essence, unblock stagnation and remove excess, strengthen efficiency and supplement deficiency, raise yang and lift the sunken. Besides, it is emphasized that caution should be taken against the drawbacks that excessive sweet may constrain the stomach, and the sweet and the warm may assist heat in the treatment of membranous nephropathy. The degree at which the spleen is supplemented and the kidney boosted should be chosen properly, and the medication contraindications should be cautioned.
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references
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Effect of Yiqi Yangyin Huoxue Formula(益气养阴活血方)on Oxidative Stress and Inflammatory Injury in Membranous Nephropathy Model Rats:Based on the NOX4-mediated SDF-1α/CXCR4 Signaling Pathway
The Preventive and Therapeutic Approach to Membranous Nephropathy Based on the Theory of "Prevention of Disease Before It Occurs"
Clinical Experience of Treating Metabolic Associated Fatty Liver Disease with Huangqi (Radix Astragali) in Lingnan (岭南) Area
Treatment of Membranous Nephropathy based on the Method of Warming the Kidney and Transforming Qi
Effect of Drug Pair Huangqi (Radix Astragali) & Baijiangcao (Herba Patriniae) on HT-29 Cell Inflammation Model by Regulating JAK1/STAT6/SOCS1 Signaling Pathway
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