LI Lihong, LIANG Fengling, LYU Zhaoshun, et al. Preliminary Construction of the "Eye-Brain" Sleep Regulation Theory Based on The Inner Canon of YellowEmperor (《黄帝内经》) and Modern Medicine[J]. Journal of Traditional Chinese Medicine, 2024, 65(20): 2092-2096.
LI Lihong, LIANG Fengling, LYU Zhaoshun, et al. Preliminary Construction of the "Eye-Brain" Sleep Regulation Theory Based on The Inner Canon of YellowEmperor (《黄帝内经》) and Modern Medicine[J]. Journal of Traditional Chinese Medicine, 2024, 65(20): 2092-2096.DOI: 10.13288/j.11-2166/r.2024.20.006.
Preliminary Construction of the "Eye-Brain" Sleep Regulation Theory Based on The Inner Canon of YellowEmperor (《黄帝内经》) and Modern Medicine
(《黄帝内经》) and modern sleep medicine on sleep and wakefulness, and initially constructed the "eye-brain" sleep regulation system. The similarities between the sleep theories in
The Inner Canon of Yellow Emperor
and modern sleep medicine research are described from three perspectives: the anatomical basis of sleep physiology, the pathogenesis of sleep disorder pathology, and the mechanism of sleep disorder treatment. It is found that the regulation of sleep and wakefulness in both medicine theories is based on the "eye" and "brain" as the main control centres, and there exists a "eye-brain" pathway to regulate sleep
and wakefulness in the human body. Based on this, the "eye-brain" sleep regulation theory is constructed, in order to find an effective way to solve the pathogenesis and treatment strategy of sleep disorders.
MORIN CM , JARRIN DC . Epidemiology of insomnia: prevalence, course, risk factors, and public health burden [J]. Sleep Med Clin , 2022 , 17 : 173 - 191 . doi: 10.1016/j.jsmc.2022.03.003 http://dx.doi.org/10.1016/j.jsmc.2022.03.003 .
LUPI D , OSTER H , THOMPSON S , et al . The acute light-induction of sleep ismediated by OPN4-based photoreception .[J]. Nat Neurosci , 2008 , 11 ( 9 ): 1068 - 1073 .
HU JX , SHI YM , ZHANG JM , et al . Melanopsin retinal ganglion cells mediate light-promoted brain development [J]. Cell , 2022 , 185 ( 17 ): 3124 - 3137 .
VAN BOMMEL W , VAN DEN BELD G . Lighting for work: a review of visual and biological effects [J]. Lighting Res Technol , 2004 , 36 ( 4 ): 255 - 266 .
ZHANG Z , BEIER W , TENLEY H , et al . The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep [J]. Nat commun , 2021 , 12 ( 1 ): 5115 .
Mechanism of Postprandial Drowsiness and the Clinical Application under the Model of Wei Qi Circulating from Yin to Yang
Research on the Mental Model of Modern Traditional Chinese Medicine and Its Reshaping Strategies Under the Theoretical Paradigm of The Inner Canon of Yellow Emperor (《黄帝内经》)
《黄帝内经》清浊升降理论内涵及其在针刺临床中的指导意义
Formation and Theoretical Explanation of the Exterior-Interior Relationships among Channels in The Inner Canon of Yellow Emperor (《黄帝内经》)
Treatment of Amyotrophic Lateral Sclerosis by the Method of Lifting the Sunken from "Deficiency,Toxin, Wind-Heat"
Related Author
CHEN Xiangmei
WANG Conghui
SUN Boju
KANG Pengfei
SHEN Junlong
LI Jie
HUANG Yaoyao
LI Kun
Related Institution
Fengtai District Traditional Chinese Medicine Hospital
Department of Nephrology,First Medical Center of Chinese PLA General Hospital / National Key Laboratory of Kidney Diseases
School of Health Economics and Management,Nanjing University of Chinese Medicine
China Institute for History of Chinese Medicine and Medical Literature,China Academy of Chinese Medical Sciences
National Data Center of Traditional Chinese Medicine,China Academy of Chinese Medical Sciences