LI Jie,WANG Bin,LI Kecheng,et al.LI Yueqing's Experience in Treating Prostate Cancer by Stages from the Perspective of Deficiency and Stasis[J].Journal of Traditional Chinese Medicine,2024,65(22):2299-2303.
LI Jie,WANG Bin,LI Kecheng,et al.LI Yueqing's Experience in Treating Prostate Cancer by Stages from the Perspective of Deficiency and Stasis[J].Journal of Traditional Chinese Medicine,2024,65(22):2299-2303.DOI: 10.13288/j.11-2166/r.2024.22.004.
LI Yueqing's Experience in Treating Prostate Cancer by Stages from the Perspective of Deficiency and Stasis
This paper summarized Professor LI Yueqing's clinical experience in treating prostate cancer by stages from the perspective of deficiency and stasis. It is believed that the onset of prostate cancer is due to kidney deficiency, while blood stasis is the core pathogenesis, and dampness-heat, phlegm-turbid, and cancer toxins are the key pathological factors in the progression of the disease. The pathogenesis in the early stage of the disease is kidney
qi
depletion and dampness, heat and phlegm coagulation; in the middle stage, it is spleen and kidney depletion, phlegm coagulation and blood stasis; and in the late stage, the pathogenesis changes into
yin
deficiency and essence depletion, and stasis-turbid toxin obstruction. For treatment, the basic principle is to supplement and boost kidney
qi
, enrich and nourish the kidney
yin
. The main treatment methods are draining dampness, dissolving phlegm, dispelling stasis, clearing heat and resolving toxins, and the method of invigorating blood and dispelling stasis runs through the whole course of treatment. In the early stage, radical treatment is mainly used, and
Longshe Yangquan Decoction
(龙蛇羊泉汤) with modifications is supplemented to clear and drain dampness and heat. In the middle stage, androgen deprivation therapy is the basic treatment, and
Bushen Tongqiao Decoction
(补肾通窍汤) with modifications is used in combination to nourish t
he spleen and kidney, dissolve phlegm and dispel stasis. In the late stage,
Dabuyin Pills and Liuwei Dihuang Pills
(大补阴丸合六味地黄丸) with modifications is mainly used to enrich
yin
and supplement essence, resolve toxins and dissolve stasis, and prevent cancer recurrence.
SUNG H , FERLAY J , SIEGEL RL , et al . Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin , 2021 , 71 ( 3 ): 209 - 249 .
CORNFORD P , VAN DEN BERGH RCN , BRIERS E , et al . EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer. Part Ⅱ-2020 Update: treatment of relapsing and metastatic prostate cancer [J]. Eur Urol , 2021 , 79 ( 2 ): 263 - 282 .
YANG L , LIN PC . Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression [J]. Seminars Cancer Biol , 2017 , 47 : 185 - 195 . doi: 10.1016/j.semcancer.2017.08.001 http://dx.doi.org/10.1016/j.semcancer.2017.08.001 .