Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure

MA Kun; ZHONG Guanlan; ZHANG Han; HE Dandan; LI Jiani; LI Qian; GAO Shanfeng

doi:10.13288/j.11-2166/r.2024.24.014

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Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure

更新时间：2026-02-03

- Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure
- Journal of Traditional Chinese Medicine Vol. 65, Issue 24, Pages: 2593-2597(2024)
- 作者机构：
  
  1.中国中医科学院西苑医院，北京市海淀区西苑操场1号，100091
  2.天津中医药大学
  3.首都医科大学北京妇产医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2024.24.014
  CLC：
- Received：23 January 2024，
  
  Revised：2024-06-17，
  
  Published：17 December 2024
- 稿件说明：
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马堃,钟观兰,张涵等.应用补肾活血法治疗不孕症反复种植失败经验[J].中医杂志,2024,65(24):2593-2597.

MA Kun,ZHONG Guanlan,ZHANG Han,et al.Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure[J].Journal of Traditional Chinese Medicine,2024,65(24):2593-2597.
马堃,钟观兰,张涵等.应用补肾活血法治疗不孕症反复种植失败经验[J].中医杂志,2024,65(24):2593-2597. DOI： 10.13288/j.11-2166/r.2024.24.014.

MA Kun,ZHONG Guanlan,ZHANG Han,et al.Clinical Experience Applying the "Kidney-supplementing and Blood-invigorating" Method to Treat Infertility of Repeated Implantation Failure[J].Journal of Traditional Chinese Medicine,2024,65(24):2593-2597. DOI： 10.13288/j.11-2166/r.2024.24.014.

摘要

认为肾虚血瘀是反复种植失败（RIF）的关键病机，提出以补肾活血为基本治法，并以该法辅助体外受精-胚胎移植控制性超促排卵方案进行分期论治，即降调期侧重滋补肾阴兼疏肝活血，方用滋补肾阴之品合青蒿鳖甲汤加减；促排卵期侧重补养肾阳兼补血活血，自拟补肾促卵方加减；移植后侧重补肾填精，自拟五子衍宗固冲汤加减。同时确认妊娠后积极行保胎治疗，方用寿胎丸加减以补肾安胎。

Abstract

kidney deficiency and blood stasis are believed to be the key pathogenesis of recurrent implantation failure （RIF）， and therefore， it is proposed to take kidney-supplementing and blood-invigorating as the basic treatment method， and

use it by stages to assist the controlled superovulation program of in vitro fertilization-embryo transfer （IVF-ET）. The focus should be put on nourishing kidney

yin

， soothing the liver and invigorating blood during down-regulation period， using kidney

yin

-nourishing medicinals and modified

Qinghao Biejia Decoction

（青蒿鳖甲汤）. During the ovulation induction period， the focus should be put on nourishing kidney

yang

， replenishing blood， and promoting blood circulation， with self-made

Bushen Culuan Formula

（补肾促卵方） in modifications. After transplantation， it is suggested to put focus on tonifying the kidneys and replenishing essence， and self-made

Wuzi Yanzong Guchong Decoction

（五子衍宗固冲汤） in modifications can be used. At the same time， fetal protection treatment should be carried out for pregnant women， and modified

Shou Tai Pill

（寿胎丸） can be used to tonify the kidneys and calm the fetus.

关键词

Keywords

references

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