LI Yanan,XU Erping.ZHANG Lei's Experience in the Treatment of Sjögren Syndrome from the Perspective of "Same Form and Disease of Dryness and Dampness"[J].Journal of Traditional Chinese Medicine,2025,66(01):12-16.
LI Yanan,XU Erping.ZHANG Lei's Experience in the Treatment of Sjögren Syndrome from the Perspective of "Same Form and Disease of Dryness and Dampness"[J].Journal of Traditional Chinese Medicine,2025,66(01):12-16.DOI: 10.13288/j.11-2166/r.2025.01.003.
ZHANG Lei's Experience in the Treatment of Sjögren Syndrome from the Perspective of "Same Form and Disease of Dryness and Dampness"
This paper summarized professor ZHANG Lei's experience in the treatment of sjögren syndrome (SS) from the perspective of "same form and disease of dryness and dampness". It is believed that both dryness and dampness are involved as the pathological factors of SS. The important pathogenesis is that dryness and dampness are of the same form and coexist in the disease, that is, dryness and dampness can transform into each other with the same form or be concurrent in the disease. The same form of dryness and dampness includes the dryness syndrome caused by dampness and the dampness syndrome caused by dryness, which can be treated with modified
Wuling Powder
(五苓散) and modified
Ejiao Jizihuang Decoction
(阿胶鸡子黄汤), respectively. The disease of both dryness and dampness includes lung dryness with spleen dampness, stomach dryness with spleen dampness, liver dryness with spleen dampness, and kidney dryness with spleen dampness syndrome, which can be treated with modified
NOCTURNE G , MARIETTE X . Sjögren syndrome-associated lymphomas:an update on pathogenesis and management [J]. Br J Haematol , 2015 , 168 ( 3 ): 317 - 327 .
BAER AN , GOTTENBERG JE , CLAIR EWST , et al . Efficacy and safety of abatacept in active primary sjögren's syndrome:results of a phase Ⅲ,randomised,placebo-controlled trial [J]. Ann Rheum Dis , 2021 , 80 ( 3 ): 339 - 348 .
WANG SQ , ZHANG LW , WEI P , et al . Is hydroxychloroquine effective in treating primary sjögren's syndrome:a systematic review and meta-analysis [J]. BMC Musculoskelet Disord , 2017 , 18 ( 1 ): 186 .