.Key Issues and Innovative Development in the Key Discipline of Traditional Chinese Medicine Oncology[J].Journal of Traditional Chinese Medicine,2025,66(03):222-227.
.Key Issues and Innovative Development in the Key Discipline of Traditional Chinese Medicine Oncology[J].Journal of Traditional Chinese Medicine,2025,66(03):222-227.DOI: 10.13288/j.11-2166/r.2025.03.002.
Key Issues and Innovative Development in the Key Discipline of Traditional Chinese Medicine Oncology
The key discipline of traditional Chinese medicine (TCM) oncology has achieved remarkable results in the establishment and development of theoretical systems, clinical efficacy research, mechanism exploration, talent cultivation, team building, and the growth of academic organizations and alliances. However, there remain problems such as lack of sufficient clinical evidence, improvement of the development of new TCM drugs with efficacy advantages, further elucidation of the mechanisms underlying TCM-based tumor prevention and treatment, and enhan-cement of the research system for TCM oncology and research capabilities. Therefore, this paper proposes five critical directions, including advancing high-quality evidence-based research on TCM for tumor prevention and treatment, building brand recognition for TCM-based anti-tumor products, establishing key technological systems for TCM oncology research, ensuring theoretical innovation and continuity in TCM oncology, and creating a national-level innovation platform to support TCM oncology. By prioritizing scientific and technological innovation as the core of new productive forces, the high-quality development of TCM oncology as a key discipline can be further promoted.
ZHANG X , GUO Q , LI C , et al . Immortal time bias-corrected effectiveness of traditional Chinese medicine in non-small cell lung cancer (C-EVID): a prospective cohort study [J]. Front Oncol , 2022 , 12 : 845613 . doi: 10.3389/fonc.2022.845613 http://dx.doi.org/10.3389/fonc.2022.845613 .
XU Y , MAO JJ , SUN L , et al . Association between use of traditional Chinese medicine herbal therapy and survival outcomes in patients with stage Ⅱ and Ⅲcolorectal cancer: a multicenter prospective cohort study [J]. J Natl Cancer Inst Monogr , 2017 ( 52 ): lgx015 .
CHEN YX , GAO QY , ZOU TH , et al . Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study [J]. Lancet Gastroenterol Hepatol , 2020 , 5 ( 3 ): 267 - 275 .
HERSHMAN DL , UNGER JM , GREENLEE H , et al . Effect of acupuncture vs sham acupuncture or waitlist control on joint pain related to aromatase inhibitors among women with early-stage breast cancer: a rando-mized clinical trial [J]. JAMA , 2018 , 320 ( 2 ): 167 - 176 .
SHEN J , WENGER N , GLASPY J , et al . Electroacupuncture for control of myeloablative chemotherapy-induced emesis: a randomized controlled trial [J]. JAMA , 2000 , 284 ( 21 ): 2755 - 2761 .
BAO T , PATIL S , CHEN C , et al . Effect of acupuncture vs sham procedure on chemotherapy-induced peripheral neuropathy symptoms: a randomized clinical trial [J]. JAMA Netw Open , 2020 , 3 ( 3 ): e200681 .
WANG W , LIU Y , YANG X , et al . Effects of electroacupuncture for opioid-induced constipation in patients with cancer in China: a randomized clinical trial [J]. JAMA Netw Open , 2023 , 6 ( 2 ): e230310 .
TAKEMURA N , CHEUNG DST , FONG DYT , et al . Effectiveness of aerobic exercise and Tai Chi interventions on sleep quality in patients with advanced lung cancer: a randomized clinical trial [J]. JAMA Oncol , 2024 , 10 ( 2 ): 176 - 184 .
LI R , ZHOU J , WU X , et al . Jianpi Jiedu recipe inhi-bits colorectal cancer liver metastasis via regulating ITGBL1-rich extracellular vesicles mediated activation of cancer-associated fibroblasts [J]. Phytomedicine , 2022 , 100 : 154082 . doi: 10.1016/j.phymed.2022.154082 http://dx.doi.org/10.1016/j.phymed.2022.154082 .
GE H , XU C , CHEN H , et al . Traditional Chinese medicines as effective reversals of epithelial-mesenchymal transition induced-metastasis of colorectal cancer: mole-cular targets and mechanisms [J]. Front Pharmacol , 2022 , 13 : 842295 . doi: 10.3389/fphar.2022.842295 http://dx.doi.org/10.3389/fphar.2022.842295 .
GOU H , SU H , LIU D , et al . Traditional medicine Pien Tze Huang suppresses colorectal tumorigenesis through restoring gut microbiota and metabolites [J]. Gastroenterology , 2023 , 165 ( 6 ): 1404 - 1419 .
YUAN L , YANG L , ZHANG S , et al . Development of a tongue image-based machine learning tool for the diagnosis of gastric cancer: a prospective multicentre clinical cohort study [J]. EClinicalMedicine , 2023 , 57 : 101834 . doi: 10.1016/j.eclinm.2023.101834 http://dx.doi.org/10.1016/j.eclinm.2023.101834 .
GAO W , SUN HX , XIAO H , et al . Combining metabolomicsand transcriptomics to characterize tanshinone biosynthesis in Salvia Miltiorrhiza [J]. BMC Genomics , 2014 , 15 : 73 . doi: 10.1186/1471-2164-15-73 http://dx.doi.org/10.1186/1471-2164-15-73 .
Ensuring and Re-evaluation the Definitive Efficacy of Protected Traditional Chinese Medicinal Products under the Framework of the Regulations on the Protection of Traditional Chinese Medicinal Varieties
Current Status of Clinical and Basic Research on Traditional Chinese Medicine for Functional Constipation
Real-World Study on the Clinical Efficacy of Different Medication Regimens of Wangbi Tablet (尪痹片) in the Treatment of Knee Osteoarthritis
Reflection on the Discipline Construction of Traditional Chinese Medicine Cardio-Oncology
Clinical Observation on Guanxinping Tablet for 33 Cases of Coronary Heart Disease and Angina Pectoris
Related Author
SHAO Mingyi
LIANG Jinxiao
WANG Xuehan
REN Rui
LIU Yanan
ZHAO Ruixia
LI Rui
CUI Hongyan
Related Institution
Henan University of Chinese Medicine
The First Affiliated Hospital of Henan University of Chinese Medicine
Xiyuan Hospital,China Academy of Chinese Medical Sciences
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine