CHEN Hanjiang,RONG Ping,ZHANG Xilian,et al.Prevention and Treatment Ideas of Epileptogenesis in Children under the Perspective of Traditional Chinese Medicine and Western Medicine[J].Journal of Traditional Chinese Medicine,2025,66(03):251-255.
CHEN Hanjiang,RONG Ping,ZHANG Xilian,et al.Prevention and Treatment Ideas of Epileptogenesis in Children under the Perspective of Traditional Chinese Medicine and Western Medicine[J].Journal of Traditional Chinese Medicine,2025,66(03):251-255.DOI: 10.13288/j.11-2166/r.2025.03.007.
Prevention and Treatment Ideas of Epileptogenesis in Children under the Perspective of Traditional Chinese Medicine and Western Medicine
Epileptogenesis is a dynamic process of gradual progression from normal developing brain to pathological epileptic brain, which is the latent and budding stage of epilepsy. Combining the understanding of epileptogenesis in children from Western medicine and traditional Chinese medicine (TCM), we proposed that the viewpoints of constitutional transformation, phlegm pathogen inducing epilepsy, and brain collateral damage, which correspond to key pathological mechanisms, namely gene polymorphism, immunoinflammation, and microvascular dysfunction of the blood-brain barrier, respectively. Based on these insights, strategies for prevention and treatment of epileptogenesis in children, as well as potential research directions are explored.
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