Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress
|更新时间:2025-03-27
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Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress
Journal of Traditional Chinese MedicineVol. 66, Issue 7, Pages: 690-694(2025)
DI Zeju,YANG Suqing,ZHANG Qiong,et al.Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress[J].Journal of Traditional Chinese Medicine,2025,66(07):690-694.
DI Zeju,YANG Suqing,ZHANG Qiong,et al.Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress[J].Journal of Traditional Chinese Medicine,2025,66(07):690-694.DOI: 10.13288/j.11-2166/r.2025.07.007.
Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress
Oxidative stress can activate multiple inflammatory pathways, triggering and exacerbating psoriasis lesions. In traditional Chinese medicine (TCM), blood turbidity refers to a pathological condition in which harmful stimuli or unhealthy lifestyle habits lead to an accumulation of impurities in the blood, resulting in increased viscosity and impaired circulation. Based on the correlation between blood turbidity theory in TCM and the pathological changes of oxidative stress in modern medicine, this paper explored the TCM diagnosis and treatment of psoriasis, proposing that spleen deficiency with latent turbidity is the fundamental cause of the disease. The pathological progression of psoriasis was outlined as follows, spleen deficiency with latent turbidity→phlegm and blood stasis intertwining→internal generation of toxic pathogens. Targeting oxidative stress, the study suggests syndrome differentiation and treatment with angle medicine (角药, means three medicinals combination). The treatment strategy divided into three stages. For early stage, strengthening the spleen and directing the turbid downward, emphasizing prevention before onset, with angle medicine of Huangqi (
Astragali Radix
) - Fuling (
Poria
) - Baizhu (
Atractylodis macrocephalae rhizoma
) to treat; for middle stage, resolving phlegm and dispersing blood stasis, preventing disease progression, if patient with more phlegm syndrome treated with angle medicine of Banxia (
Pinelliae rhizoma
) - Chenpi (
Citri reticulatae pericarpium
) - Zhexie (
Alismatis rhizoma
), and if patient with more stasis syndrome treated with Zicao (
Arnebiae Radix
) - Jixueteng (
Spatholobi caulis
) - Shouwuteng (
Polygonum multiflorum Thunb
); for late stage, resolving toxins and dispelling pathogens, balancing both attack and supplementation, with Quanxie (
Scorpio
) - Tufuling (
Smilacis glabrae rhizoma
) - Shudihuang (
Rehmanniae radix praeparata
) to treat.
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references
FORMAN HJ , ZHANG H , Targeting oxidative stress in disease : promise and limitations of antioxidant therapy [J]. Nat Rev Drug Discov , 2021 , 20 ( 9 ): 689 - 709 .
RIJNVAN MJE , SCHUT AF , AULCHENKO YS , et al . Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes [J]. J HYPERTENS , 2007 , 25 ( 3 ): 565 - 570 .
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Effect of Dingchuan Granule (定喘颗粒) on Lung Tissue Oxidative Stress and Nrf2/Keap1/HO-1/NQO1 Pathway in Respiratory Syncytial Virus Pneumonia Model Rats
Related Author
YUAN Zhenhua
JIANG Yingying
CAI Mingyang
ZHU Rongxin
REN Xianqing
GUO Xiaoxiao
SONG Chundong
ZHANG Hanhan
Related Institution
Children Hospital,First Affiliated Hospital of Henan University of Chinese Medicine
Pediatric Medical College,Henan University of Chinese Medicine
Department of Pediatrics,First Affiliated Hospital of Henan University of Chinese Medicine
College of Pediatrics,Henan University of Chinese Medicine