ZHOU Ziyi,FENG Zhe,ZHOU Xueping.Research Strategies for the Traditional Chinese Medicine Pathomechanism Syndrome Differentiation System from the Perspective of Systems Thinking[J].Journal of Traditional Chinese Medicine,2025,66(08):765-768.
ZHOU Ziyi,FENG Zhe,ZHOU Xueping.Research Strategies for the Traditional Chinese Medicine Pathomechanism Syndrome Differentiation System from the Perspective of Systems Thinking[J].Journal of Traditional Chinese Medicine,2025,66(08):765-768.DOI: 10.13288/j.11-2166/r.2025.08.001.
Research Strategies for the Traditional Chinese Medicine Pathomechanism Syndrome Differentiation System from the Perspective of Systems Thinking
Given the limitations of traditional scientific research methods in revealing the complex and dynamic evolution of disease pathomechanisms, this paper analyzes the current state and challenges of the traditional Chinese medicine (TCM) pathomechanism syndrome differentiation system within the framework of systems thinking. The challenges include insufficient experimental models, low data standardization, complex nonlinear characteristics, and difficulties in integrating expert experience. By leveraging qualitative-quantitative comprehensive integration methods, this paper proposes specific research strategies, including constructing qualitative models of pathomechanism evolution, employing mathematical models for validation and quantitative analysis to reveal pathomechanism patterns, and incorporating a "human-centered" approach to achieve human-machine collaboration. These strategies aim to provide insights for the modernization and development of a new TCM pathomechanism syndrome differentiation system.