A Randomized Controlled Trial of Stone Needle Thermocompression and Massage for Treating Chronic Musculoskeletal Pain in the Shoulder and Back：A Secondary Analysis of Muscle Elasticity as a Mediator

QIAN Jingjing; LI Yuanjing; LI Li; XI Yawei; WANG Ying; GUO Cuihua; ZHOU Jiayan; SUN Yaxuan; LIU Shu; YANG Guangjing; YUAN Na; YANG Xiaofang

doi:10.13288/j.11-2166/r.2025.09.011

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A Randomized Controlled Trial of Stone Needle Thermocompression and Massage for Treating Chronic Musculoskeletal Pain in the Shoulder and Back：A Secondary Analysis of Muscle Elasticity as a Mediator

更新时间：2025-04-30

- A Randomized Controlled Trial of Stone Needle Thermocompression and Massage for Treating Chronic Musculoskeletal Pain in the Shoulder and Back：A Secondary Analysis of Muscle Elasticity as a Mediator
  增强出版
- Journal of Traditional Chinese Medicine Vol. 66, Issue 9, Pages: 935-940(2025)
- 作者机构：
  
  1.中国中医科学院广安门医院，北京市西城区北线阁5号，100053
  2.美国斯坦福大学医学院
  3.美国哈佛大学公共卫生学院
  4.河南中医药大学第一附属医院
  5.重庆市中医院
  6.中国中医科学院望京医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.09.011
  CLC：
- Received：30 November 2024，
  
  Revised：2025-03-06，
  
  Published：02 May 2025
- 稿件说明：
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钱晶晶,李远竞,李莉等.砭石热熨推拿治疗肩背部慢性肌肉骨骼疼痛的随机对照试验——肌肉弹性中介作用的二次分析[J].中医杂志,2025,66(09):935-940.

QIAN Jingjing,LI Yuanjing,LI Li,et al.A Randomized Controlled Trial of Stone Needle Thermocompression and Massage for Treating Chronic Musculoskeletal Pain in the Shoulder and Back：A Secondary Analysis of Muscle Elasticity as a Mediator[J].Journal of Traditional Chinese Medicine,2025,66(09):935-940.
钱晶晶,李远竞,李莉等.砭石热熨推拿治疗肩背部慢性肌肉骨骼疼痛的随机对照试验——肌肉弹性中介作用的二次分析[J].中医杂志,2025,66(09):935-940. DOI： 10.13288/j.11-2166/r.2025.09.011.

QIAN Jingjing,LI Yuanjing,LI Li,et al.A Randomized Controlled Trial of Stone Needle Thermocompression and Massage for Treating Chronic Musculoskeletal Pain in the Shoulder and Back：A Secondary Analysis of Muscle Elasticity as a Mediator[J].Journal of Traditional Chinese Medicine,2025,66(09):935-940. DOI： 10.13288/j.11-2166/r.2025.09.011.

摘要

目的

探讨砭石热熨推拿对比氟比洛芬凝胶贴膏在改善肩背部慢性肌肉骨骼疼痛方面的有效性，并通过中介作用分析其可能的作用机制。

方法

将120例肩背部慢性肌肉骨骼疼痛患者随机分为砭石热熨推拿组与氟比洛芬凝胶贴膏组，每组60例。砭石热熨推拿组给予砭石热熨推拿，每次30 min，每周3次；氟比洛芬凝胶贴膏组给予氟比洛芬凝胶贴膏每日2次。两组均治疗2周。主要疗效指标：使用整体疼痛评估量表（GPS）评估治疗结束2周后疼痛改善程度。中介作用测量：使用肌骨超声评价治疗前、治疗2周后浅层与深层肌肉弹性的改变。

结果

砭石热熨推拿组与氟比洛芬凝胶贴膏组在治疗结束2周后改善肌肉骨骼疼痛方面差异具有统计学意义，对疼痛病程的混杂因素校正后，两组间均值差为-8.8［95%

（-18.2，-0.7），

＜0.05］。这一疗效部分通过改变深层肌肉弹性发挥作用，中介作用效应量为-1.5［95%

（-2.0，-0.9），

=0.024］，占总疗效的17.9%。

结论

砭石热熨推拿可有效缓解肩背部慢性肌肉骨骼疼痛患者的疼痛程度，并通过改变深层肌肉弹性对治疗效果发挥中介作用。

Abstract

Objective

To evaluate the effectiveness of stone needle thermocompression and massage compared to flurbiprofen gel patch in relieving chronic musculoskeletal pain in the shoulder and back， and to explore the potential mediating mechanism through muscle elasticity.

Methods

A total of 120 patients with chronic musculoskeletal pain in the shoulder and back were randomly assigned to either stone needle group or flurbiprofen group， with 60 patients in each. The stone needle group received stone needle thermocompression and massage for 30 minutes， three times per week； the flurbiprofen group received flurbiprofen gel patch twice daily. Both groups were treated for 2 weeks. Pain improvement， as the primary outcome， was assessed using the Global Pain Scale （GPS） at baseline， after 2 weeks of treatment， and again 2 weeks post-treatment. To explore potential mechanisms， a mediator analysis was conducted by measuring changes in superficial and deep muscle elasticity using musculoskeletal ultrasound at baseline and after the 2-week treatment period.

Results

The stone needle group showed significantly greater pain relief than the flurbiprofen group 2 weeks post-treatment. After adjusting for confounders related to pain duration， the between-group mean difference was -8.8 ［95%

（-18.2， -0.7），

＜0.05］. Part of the therapeutic effect was mediated by changes in deep muscle el

asticity， with a mediation effect size of -1.5 ［95%

（-2.0， -0.9），

= 0.024］， accounting for 17.9% of the total effect.

Conclusion

Stone needle thermocompression and massage can effectively relieve chronic musculoskeletal pain in the shoulder and back， partly through a mediating effect of improved deep muscle elasticity.

关键词

Keywords

references

World Health Organization . Musculoskeletal health ［EB/OL］. （ 2022-07-14 ）［ 2024-04-01 ］. https：//www.who.int/news-room/fact-sheets/detail/musculoskeletal-conditions https://www.who.int/news-room/fact-sheets/detail/musculoskeletal-conditions .

WILLIAMS A ， KAMPER SJ ， WIGGERS JH ， et al . Musculoskeletal conditions may increase the risk of chronic disease： a systematic review and meta-analysis of cohort studies ［J］. BMC Med ， 2018 ， 16 （ 1 ）： 167 .

HARTVIGSEN J ， HANCOCK MJ ， KONGSTED A ， et al . What low back pain is and why we need to pay attention ［J］. Lancet ， 2018 ， 391 （ 10137 ）： 2356 - 2367 .

MITCHELL C ， ADEBAJO A ， HAY E ， et al . Shoulder pain： diagnosis and management in primary care ［J］. BMJ ， 2005 ， 331 （ 7525 ）： 1124 - 1128 .

LUIME JJ ， KOES BW ， HENDRIKSEN IJ ， et al . Prevalence and incidence of shoulder pain in the general population：a systematic review ［J］ Scand J Rheumatol ， 2004 ， 33 （ 2 ）： 73 - 81 .

EI-TALLAWY SN ， NALAMASU R ， SALEM GI ， et al . Management of musculoskeletal pain： an update with emphasis on chronic musculoskeletal pain ［J］. Pain Ther ， 2021 ， 10 （ 1 ）： 181 - 209 .

郭翠花，李莉，郭敬，等 . 砭石热熨加按揉经穴治疗项背肌筋膜炎的随机对照试验［J］. 北京中医药， 2024 ， 43 （ 8 ）： 857 - 860 .

HARRISON JE ， WEBER S ， JAKOB R ， et al . ICD-11： an international classification of diseases for the twenty-first century ［J］. BMC Med Inform Decis Mak ， 2021 ， 21 （ Suppl 6 ）： 206 .

国家中医药管理局 . 中医病证诊断疗效标准［M］. 南京：南京大学出版社， 1994 ： 187 .

中国疼痛学专家组 . 疼痛评估量表应用的中国专家共识（2020版）［J］. 中华疼痛学杂志， 2020 ， 16 （ 3 ）： 177 - 187 .

GENTILE DA ， WOODHOUSE J ， LYNCH P ， et al . Reliability and validity of the global pain scale with chronic pain sufferers ［J］. Pain Physician ， 2011 ， 14 （ 1 ）： 61 - 70 .

范希然，李多多，王双双，等 . 推拿手法治疗骨骼肌肉疼痛影响因素的质性研究［J］. 中国全科医学， 2023 ， 26 （ 2 ）： 219 - 224 .

仉培臻，郭锰 . 项背肌筋膜炎发病机制及治疗研究进展［J］. 亚太传统医药， 2025 ， 21 （ 1 ）： 204 - 209 .

BENNARDO L ， FUSCO I ， CUCITI C ， et al ． Microwave therapy for cellulite： an effective non-invasive treatment ［J］. J Clin Med ， 2022 ， 11 （ 3 ）： 515 ．

BOKU H ， KANEKO M ， YAMADA Y ， et al ． Microwave focal therapy of prostate cancer： a non-clinical study and exploratory clinical trial ［J］. BJU Int ， 2022 ， 130 （ 6 ）： 776 - 785 ．

秦谊，胡晓玲，郑媛媛，等 . 电热砭石温熨疗法对颈性眩晕临床疗效观察［J］. 中医药学报， 2020 ， 48 （ 4 ）： 50 - 53 .

段青松，程立，夏能光 . 经皮神经电刺激联合氟比洛芬凝胶贴膏对脑卒中后肩手综合征患者运动能力及DAR、BSI、FA值的影响［J］. 临床医学工程， 2021 ， 28 （ 9 ）： 1155 - 1156 .

吴紫阳，程吟楚，易湛苗，等 . 氟比洛芬凝胶贴膏治疗膝骨关节炎的药品临床综合评价［J］. 中国医药， 2023 ， 18 （ 2 ）： 260 - 264 .

纪泉，易端，王建业，等 . 老年患者慢性肌肉骨骼疼痛管理中国专家共识（2019）［J］. 中华老年病研究电子杂志， 2019 ， 6 （ 2 ）： 28 - 34 .

康鹏德，黄泽宇，李庭，等 . 肌肉骨骼系统慢性疼痛管理专家共识［J］. 中华骨与关节外科杂志， 2020 ， 13 （ 1 ）： 8 - 16 .

温忠麟，方杰，谢晋艳，等 . 国内中介效应的方法学研究［J］. 心理科学进展， 2022 ， 30 （ 8 ）： 1692 - 1702 .

郝振民，郭振宁，邓宇光，等 . 肌骨超声、SMI联合SWE技术在观察NLBP患者相关肌肉特征变化中的应用［J］. 影像科学与光化学， 2023 ， 41 （ 1 ）： 79 - 83 .

张其明，鲍赛荣，单莎瑞，等 . 电动深层肌肉刺激慢性非特异性腰痛患者竖脊肌的张力及硬度变化的数字化肌肉检测［J］. 中国组织工程研究， 2023 ， 27 （ 8 ）： 1250 - 1256 .

陈进，李加斌，顾铭星，等 . 深层肌肉刺激慢性非特异性腰痛患者腰肌表面肌电变化与步态时空及动力学的参数变化［J］. 中国组织工程研究， 2022 ， 26 （ 18 ）： 2894 - 2899 .

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