LU Zhiyuan,LIN Lili,DAI Qigang,et al.Staged-Based Differentiation and Treatment of Pediatric Pertussis by Regulating Qi and Relieving Cough[J].Journal of Traditional Chinese Medicine,2025,66(10):1060-1064.
LU Zhiyuan,LIN Lili,DAI Qigang,et al.Staged-Based Differentiation and Treatment of Pediatric Pertussis by Regulating Qi and Relieving Cough[J].Journal of Traditional Chinese Medicine,2025,66(10):1060-1064.DOI: 10.13288/j.11-2166/r.2025.10.014.
Staged-Based Differentiation and Treatment of Pediatric Pertussis by Regulating Qi and Relieving Cough
It is considered that the fundamental pathogenesis of pediatric pertussis lies in the dysfunction of lung
qi
, and it is advocated to treat the disease with the method of regulating
qi
and relieving cough. Clinically, the disease is divided into three stages for syndrome differentiation and treatment, initial coughing stage, spasmodic coughing stage, and prolonged coughing stage. In the initial coughing stage, the pathogenesis involves invasion by external pathogens and failure of lung
qi
to disperse; the treatment principle is to release the exterior, expel pathogens, ventilate the lungs, and relieve cough. For cold patterns, modified
San'ao Decoction
(三拗汤) is prescribed; for heat type, a self-formulated
Qingqi Xuanfei Decoction
(清气宣肺汤) is used. In the spasmodic coughing stage, the pathogenesis is the congealing of phlegm and fire with impaired lung purification; the treatment focuses on eliminating phlegm, dredging the meridians, purging the lungs, and relieving cough. Mild cases are treated with a self-formulated
Tongluo Xiefei Decoction
(通络泻肺汤), while
severe cases are treated with a modified combination of
Maxing Shigan Decoction
(麻杏石甘汤) and
Qianjin Weijing Decoction
(千金苇茎汤). In the prolonged coughing stage, the pathogenesis involves the depletion of
qi
and
yin
and latent pathogens in a weakened lung; the treatment aims to tonify
qi
, nourish
yin
, moisten the lungs, and eliminate residual pathogens. For lung
FENG Y , CHIU CH , HEININGER U , et al . Emerging macrolide resistance in Bordetella pertussis in mainland China:findings and warning from the global pertussis initiative [J]. Lancet Reg Health West Pac , 2021 , 8 : 100098 . doi: 10.1016/j.lanwpc.2021.100098 http://dx.doi.org/10.1016/j.lanwpc.2021.100098 .
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Related Institution
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