Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency <italic style="font-style: italic">Qi</italic> Retention and Stagnation"

LI Yunze; ZONG Huiqi; LIU Hongxu; LI Mingxuan; LI Xiang

doi:10.13288/j.11-2166/r.2025.12.013

您当前的位置：

首页 >

文章列表页 >

Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency Qi Retention and Stagnation"

更新时间：2025-06-13

- Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency Qi Retention and Stagnation"
- Journal of Traditional Chinese Medicine Vol. 66, Issue 12, Pages: 1273-1276(2025)
- 作者机构：
  
  1.首都医科大学附属北京中医医院，北京市东城区美术馆后街23号，100010
  2.北京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.12.013
  CLC：
- Received：13 December 2024，
  
  Revised：2025-03-14，
  
  Published：17 June 2025
- 稿件说明：
移动端阅览
李昀泽,宗慧琪,刘红旭等.从“虚气留滞”防治PCI术后冠状动脉微血管功能障碍[J].中医杂志,2025,66(12):1273-1276.

LI Yunze,ZONG Huiqi,LIU Hongxu,et al.Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency Qi Retention and Stagnation"[J].Journal of Traditional Chinese Medicine,2025,66(12):1273-1276.
李昀泽,宗慧琪,刘红旭等.从“虚气留滞”防治PCI术后冠状动脉微血管功能障碍[J].中医杂志,2025,66(12):1273-1276. DOI： 10.13288/j.11-2166/r.2025.12.013.

LI Yunze,ZONG Huiqi,LIU Hongxu,et al.Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency Qi Retention and Stagnation"[J].Journal of Traditional Chinese Medicine,2025,66(12):1273-1276. DOI： 10.13288/j.11-2166/r.2025.12.013.

摘要

认为“虚气留滞”是经皮冠状动脉介入治疗（PCI）术后冠状动脉微血管功能障碍（CMD）的根本病机。PCI术前多心脉瘀阻较重，导致络脉失充，正气不足，气血津液运行无力，使心络易滞易瘀，痰瘀内生；术后易正伤气虚，引起气血津液失运，进而导致血瘀、痰浊留滞生变，化热生风，损伤心体。提出PCI术前防病当益气充络、逐瘀化痰，以改善心络“虚气”，预防术后“留滞”；术后调治当益气护络、祛邪防变，既避免正气损伤加重虚滞，又祛邪通络截断病机，以防“留滞”生变。

Abstract

It is believed that "deficiency

retention and stagnation" is the fundamental pathogenesis of coronary microvascular dysfunction （CMD） after percutaneous coronary intervention （PCI）. Patients often have severe coronary vessel congestion before PCI， leading to emptiness in the heart's collaterals， which results in deficiency of healthy

， poor movement of blood and body fluids， so the heart collaterals are susceptible to stagnation and stasis，then phlegm and stasis generate； after PCI， it is easy to damage the healthy

then lead to

deficiency， causing

， blood， and body fluids fail to transport， thereby leading to blood stasis and phlegm turbidity retention， generating heat and wind to damage the heart and body. It is proposed that the prevention before PCI should replenish

and collaterals， expel blood

stasis and resolve phlegm， to support "deficient

" in heart collaterals and prevent "stagnation" after PCI. Postoperative management should focus on replenishing

and protecting the collaterals， eliminating pathogen and controlling development， so as to avoid exacerbating deficiency and stagnation by damaging healthy

， and eliminate pathogen and unblock the collaterals to interrupt the pathogenesis， which prevent "retention and stagnation" from changes.

关键词

Keywords

references

中华医学会心血管病学分会 . 冠状动脉微血管疾病诊断和治疗中国专家共识（2023版）［J］. 中华心血管病杂志， 2024 ， 52 （ 5 ）： 460 - 492 .

XIE J ， HE Y ， JI H ， et al . Impact of plaque characteristics on percutaneous coronary intervention-related microvascular dysfunction： insights from angiographic microvascular resistance and intravascular ultrasound ［J］. Quant Imaging Med Surg ， 2023 ， 13 （ 9 ）： 6037 - 6047 .

CANU M ， KHOURI C ， MARLIERE S ， et al . Prognostic significance of severe coronary microvascular dysfunction post-PCI in patients with STEMI： a systematic review and meta-analysis ［J］. PLoS One ， 2022 ， 17 （ 5 ）： e0268330 .

NISHI T ， MURAI T ， CICCARELLI G ， et al . Prognostic value of coronary microvascular function measured immediately after percutaneous coronary intervention in stable coronary artery disease： an international multicenter study ［J］. Circ Cardiovasc Interv ， 2019 ， 12 （ 9 ）： e007889 .

MARINESCU MA ， LÖFFLER AI ， OUELLETTE M ， et al . Coronary microvascular dysfunction， microvascular angina， and treatment strategies ［J］. JACC Cardiovasc Imaging ， 2015 ， 8 （ 2 ）： 210 - 220 .

王澳龙，卫靖靖，于瑞，等 . 经皮冠状动脉介入术术后冠脉微循环障碍的中医药治疗研究概述［J］. 中华中医药学刊， 2024 ， 42 （ 2 ）： 136 - 141 .

中华中医药学会冠状动脉微血管病中医诊疗指南项目组 . 冠状动脉微血管病中医诊疗指南［J］. 中医杂志， 2023 ， 64 （ 21 ）： 2261 - 2268 .

《冠状动脉微血管病中西医结合诊疗指南》项目组 . 冠状动脉微血管病中西医结合诊疗指南［J］. 中国中西医结合杂志， 2023 ， 43 （ 9 ）： 1029 - 1039 .

尚菊菊，刘红旭，周琦，等 . 参元益气活血胶囊对择期PCI围手术期心肌保护以及血清GSH、MPO水平影响的临床研究［J］. 北京中医药， 2017 ， 36 （ 12 ）： 1098 - 1102 .

贾思涵，连妍洁，尚菊菊，等 . 从“虚气留滞”论治心房颤动［J］. 中医杂志， 2024 ， 65 （ 12 ）： 1235 - 1239 .

黄世敬，王永炎 . 缺血性脑白质病变“虚气留滞”病机探讨［J］. 北京中医药大学学报， 2011 ， 34 （ 8 ）： 513 - 516 .

李明轩，李红典，刘红旭，等 . 基于五行学说论治冠状动脉微循环障碍［J］. 中华中医药杂志， 2024 ， 39 （ 4 ）： 1727 - 1730 .

魏聪，贾振华，常丽萍 . 中医络病学科研究回顾与展望［J］. 中医杂志， 2015 ， 56 （ 22 ）： 1971 - 1975 .

张辰浩，刘冠男，孔晓琳，等 . 801例冠心病患者PCI术后中医证候及相关因素的回顾性研究［J］. 中医杂志， 2018 ， 59 （ 20 ）： 1766 - 1770 .

赵烨婧，彭红玉，刘建勋，等 . 急性冠脉综合征患者介入治疗前后气滞血瘀气虚血瘀证候演变规律及预后分析［J］. 中国中西医结合杂志， 2023 ， 43 （ 2 ）： 162 - 168 .

李昀泽，刘子豪，刘红旭，等 . 张锡纯《医学衷中参西录》治疗血瘀证原创处方用药规律分析［J］. 世界中西医结合杂志， 2024 ， 19 （ 2 ）： 255 - 260，265 .

朱晨阳，胡骏，刘兰椿，等 . 基于“血-脉-心络”共病理论探讨虫类药在冠状动脉微血管功能障碍的应用［J］. 中国实验方剂学杂志， 2024 ， 30 （ 1 ）： 176 - 185 .

赵文景，赵凯声，段昱方，等 . 张炳厚运用虫类药经验总结［J］. 北京中医药， 2010 ， 29 （ 11 ）： 826 - 828 .

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Association between Triglyceride-Glucose Index and Major Adverse Cardiovascular Events Risk in Coronary Heart Disease Patients with Blood Stasis Syndrome after Percutaneous Coronary Intervention

Comparative Study on Effect of Yiqi Liangxue Shengji Formula （益气凉血生肌方） and Atorvastatin Tablets on Vascular Injury and Differences in Serum Metabolites in Abdominal Aortic Balloon Injury Model Rats

Discussion on No-reflow Phenomenon after Percutaneous Coronary Intervention Based on “Collateral Disease and Sweat Pore”

Effects of Jianpi Yiqi Huatan Formula on Left Ventricular Remodeling and Cardiac Function in Acute Myocardial Infarction Patients after Percutaneous Coronary Intervention

Effects of Wenxin Grannle （稳心颗粒） on the Expression of Circulating Micro RNA-1 in Patients with Acute ST-segment Elevation Myocardial Infarction

Related Author

TAN Yuqing

XUE Tiantian

YANG Deshuang

XIE Zicong

HUANG Li

LI Jun

YU Lintong

TAO Shiyi

Related Institution

Beijing University of Chinese Medicine

Guang'anmen Hospital，China Academy of Chinese Medical Sciences

Japan Friendship Hospital

Dongzhimen Hospital，Beijing University of Chinese Medicine

Beijing University of Chinese Medicine Third Affiliated Hospital

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰

Prevention and Treatment of Post-Percutaneous Coronary Intervention Coronary Microvascular Dysfunction from the Perspective of "Deficiency Qi Retention and Stagnation"

DOI：10.13288/j.11-2166/r.2025.12.013

摘要

Abstract

关键词

Keywords

references