Experience of LI Diangui in Treating Gastroesophageal Reflux Disease Based on the Theory of Turbidity-Toxin in Liver

LIANG Shiyue; GAO Mengqi; LIU Yansheng; BAI Minan; LOU Yingying

doi:10.13288/j.11-2166/r.2025.16.003

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Experience of LI Diangui in Treating Gastroesophageal Reflux Disease Based on the Theory of Turbidity-Toxin in Liver

更新时间：2025-08-13

- Experience of LI Diangui in Treating Gastroesophageal Reflux Disease Based on the Theory of Turbidity-Toxin in Liver
- Journal of Traditional Chinese Medicine Vol. 66, Issue 16, Pages: 1640-1644(2025)
- 作者机构：
  
  1.河北中医药大学研究生学院，河北省石家庄市桥西区新石南路326号，050200
  2.河北中医药大学第一附属医院
  3.河北省浊毒证重点实验室
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.16.003
  CLC：
- Received：03 September 2024，
  
  Revised：2024-10-24，
  
  Published：17 August 2025
- 稿件说明：
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梁诗悦,高梦琪,刘岩生等.李佃贵从肝之浊毒论治胃食管反流病经验[J].中医杂志,2025,66(16):1640-1644.

LIANG Shiyue,GAO Mengqi,LIU Yansheng,et al.Experience of LI Diangui in Treating Gastroesophageal Reflux Disease Based on the Theory of Turbidity-Toxin in Liver[J].Journal of Traditional Chinese Medicine,2025,66(16):1640-1644.
梁诗悦,高梦琪,刘岩生等.李佃贵从肝之浊毒论治胃食管反流病经验[J].中医杂志,2025,66(16):1640-1644. DOI： 10.13288/j.11-2166/r.2025.16.003.

LIANG Shiyue,GAO Mengqi,LIU Yansheng,et al.Experience of LI Diangui in Treating Gastroesophageal Reflux Disease Based on the Theory of Turbidity-Toxin in Liver[J].Journal of Traditional Chinese Medicine,2025,66(16):1640-1644. DOI： 10.13288/j.11-2166/r.2025.16.003.

摘要

总结李佃贵教授从肝之浊毒论治胃食管反流病的临证经验。认为浊毒内蕴、肝郁胃逆是胃食管反流病的关键病机，提出运用化浊解毒、调肝和胃法治疗。临证将胃食管反流病分为初期、中期、后期，分别运用化浊疏肝和胃方加减以理气化浊、疏肝和胃，化浊清热制酸方加减以清热泄浊解毒，益胃汤加减以益气养阴兼化浊毒，并全程注重顾护脾胃，针对病情变化进行加减用药。

Abstract

This paper summarized the clinical experience of Prof. LI Diangui in treating gastroesophageal reflux disease （GERD） based on the theory of turbidity-toxin in liver. It is believed that internal accumulation of turbidity-toxin and liver depression with stomach counterflow are the main pathogenesis of GERD， and thus the therapeutic methods of resolving turbidity and resolving toxins， regulating the liver and harmonizing the stomach are proposed. In clinical practice， GERD is divided into the early stage， middle stage and late stage. For

the early stage， the modified

Huazhuo Shugan Hewei Formula

（化浊疏肝和胃方） is used to regulate

and remove turbidity， soothe the liver and harmonize the stomach； for the middle stage， the modified

Huazhuo Qingre Zhisuan Formula

（化浊清热制酸方） is applied to clear heat， direct the turbid downward， and resolve toxins； for the late stage， the modified

Yiwei Decoction

（益胃汤） is adopted to replenish

， nourish

yin

and simultaneously resolve turbidity-toxin. Throughout the treatment process， attention should be paid to protecting the spleen and stomach， and the medication could be modified according to changes of individual condition.

关键词

Keywords

references

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