SHI Zaixiang's Clinical Experience in Using <italic style="font-style: italic">Chaihu Guizhi Ganjiang Decoction</italic> （柴胡桂枝干姜汤） to Treat High Fever in Sepsis

ZHU Tingting; LIU Yingying; CUI Hailan; REN Zhiying; SHAO Mingjing; BIAN Yan; WANG Liyan; CHEN Zhenjie; LIU Yuan

doi:10.13288/j.11-2166/r.2025.16.004

您当前的位置：

首页 >

文章列表页 >

SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis

更新时间：2025-08-13

- SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis
- Journal of Traditional Chinese Medicine Vol. 66, Issue 16, Pages: 1645-1648(2025)
- 作者机构：
  
  1.北京市第六医院，北京市东城区交道口北二条36号，100007
  2.北京市朝阳区中医医院
  3.北京市昌平区中医医院
  4.北京中医药大学
  5.中日友好医院
  6.北京中西医结合医院
  7.北京中医药大学东直门医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.16.004
  CLC：
- Received：13 August 2024，
  
  Revised：2024-12-15，
  
  Published：17 August 2025
- 稿件说明：
移动端阅览
朱婷婷,刘莹莹,崔海兰等.史载祥应用柴胡桂枝干姜汤治疗脓毒症高热经验[J].中医杂志,2025,66(16):1645-1648.

ZHU Tingting,LIU Yingying,CUI Hailan,et al.SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis[J].Journal of Traditional Chinese Medicine,2025,66(16):1645-1648.
朱婷婷,刘莹莹,崔海兰等.史载祥应用柴胡桂枝干姜汤治疗脓毒症高热经验[J].中医杂志,2025,66(16):1645-1648. DOI： 10.13288/j.11-2166/r.2025.16.004.

ZHU Tingting,LIU Yingying,CUI Hailan,et al.SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis[J].Journal of Traditional Chinese Medicine,2025,66(16):1645-1648. DOI： 10.13288/j.11-2166/r.2025.16.004.

摘要

总结史载祥教授应用柴胡桂枝干姜汤治疗脓毒症高热的临证经验。认为脓毒症的关键病机为少阳郁热、水饮内结，其临床表现高热、寒战、往来寒热乃邪热郁结少阳所致，软组织水肿及浆膜腔积液则为少阳枢机不利、水饮内结所致。临证治疗脓毒症高热当兼顾软组织水肿及浆膜腔积液，以和解少阳郁热、化饮利水为法，应用柴胡桂枝干姜汤为基本方进行灵活加减，同时指出柴胡桂枝干姜汤对于多重抗感染无效的脓毒症高热有迅速退热的作用。

Abstract

This paper summarizes Professor SHI Zaixiang's clinical experience in treating high fever caused by sepsis using

Chaihu Guizhi Ganjiang Decoction

（柴胡桂枝干姜汤）. He holds that the key pathogenesis of sepsis involves constrained heat in the

shaoyang

and internal accumulation of water and fluids. The clinical manifestations such as high fever， chills， and alternating sensations of cold and heat are attributed to pathogenic heat constrained in the

shaoyang

. Mea

nwhile， soft tissue edema and serous cavity effusions are due to

shaoyang

dysfunction and internal water retention. In clinical practice， treating sepsis-related high fever requires addressing both the

shaoyang

-constrained heat and the associated edema and effusions. The therapeutic approach focuses on harmonizing the

shaoyang

and resolving internal fluids， using

Chaihu Guizhi Ganjiang Decoction

as the base formula with flexible modifications. Professor SHI emphasizes that this formula shows a rapid antipyretic effect， particularly in cases where multiple anti-infective treatments have failed.

关键词

Keywords

references

中华医学会重症医学分会 . 中国严重脓毒症／脓毒性休克治疗指南［J］. 中华内科杂志， 2015 ， 54 （ 6 ）： 557 - 581 .

REHN M ， CHEW MS ， OLKKOLA KT ， et al . Surviving sepsis campaign： international guidelines for management of sepsis and septic shock in adults 2021： endorsement by the Scandinavian society of anaesthesiology and intensive care medicine ［J］. Acta Anaesthesiol Scand ， 2022 ， 66 （ 5 ）： 634 - 635 .

EVANS L ， RHODES A ， ALHAZZANI W ， et al . Surviving sepsis campaign：international guidelines for management of sepsis and septic shock 2021 ［J］. Crit Care Med ， 2021 ， 49 （ 11 ）： e1063 - e1143 .

熊艳，肖谦 . 血培养阳性老年脓毒症患者多重耐药菌分析［J］. 临床急诊杂志， 2022 ， 23 （ 9 ）： 643 - 648 .

胡斌，刘冰，赵浩延，等 . 中医药治疗脓毒症的研究进展［J］. 中国医药指南， 2020 ， 18 （ 22 ）： 32 - 33 .

RÜDDEL H ， THOMAS-RÜDDEL DO ， REINHART K ， et al . Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis： results of a planned secondary analysis of a cluster-randomized controlled trial ［J］. Crit Care ， 2022 ， 26 （ 1 ）： 51 .

罗松平，李拥军，董玉任，等 . 脓毒性休克液体过负荷患者反向液体复苏的临床疗效分析［J］. 临床急诊杂志， 2022 ， 23 （ 5 ）： 327 - 331 .

孙东，陈艺 . 抗生素相关性腹泻临床诊疗新进展［J］. 空军航空医学， 2024 ， 41 （ 4 ）： 352 - 355 .

金力，张新春 . 肺炎患者抗生素治疗后伪膜性肠炎发生情况及影响因素分析［J］. 临床医学工程， 2023 ， 30 （ 9 ）： 1311 - 1312 .

印佩如，倪海滨 . 中西医结合治疗脓毒症毛细血管渗漏综合征的研究进展［J］. 中国中医药现代远程教育， 2022 ， 20 （ 18 ）： 206 - 208 .

毛丽容，王释亮，谢义松 . 从胡希恕《伤寒论》学术思想探析小柴胡汤［J］. 湖南中医杂志， 2021 ， 37 （ 9 ）： 124 - 126 .

陈亦人 . 《伤寒论》求是［M］. 上海：上海科学技术出版社， 2012 ： 90 .

冯世纶，张长恩 . 经方传真（修订版）：胡希恕经方理论与实践［M］. 2版 . 北京：中国中医药出版社， 2008 ： 309 .

史载祥，黄柳华 . 经方治验百案［M］. 北京：人民卫生出版社， 2021 .

中国医师协会急诊医师分会，中国研究型医院学会休克与脓毒症专业委员会 . 中国脓毒症/脓毒性休克急诊治疗指南（2018）［J］. 中国急救医学， 2018 ， 38 （ 9 ）： 741 - 756 .

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory

YANG Zhen's Interpretation of the Wumei Pill （乌梅丸） Based on the Theory of Qi Dynamics of Ministerial Fire

Professor WEI Zixiao's Experience in Differentiating and Treating Diabetes Mellitus Complicated with Urinary Tract Infection from Taiyin （太阴） and Shaoyin （少阴）

Professor ZHOU Shaohua's Experience in Staged Treatment of Parkinson's Disease Based on the "Disease-Symptom-Syndrome Integration" Approach

Pathogenesis and Treatment Strategy of "Macrocirculation-Microcirculation" Uncoupling in Sepsis：from the Perspective of "Deep Heat，Deep Syncope"

Related Author

DING Yingge

CHEN Shilong

WANG Shurui

WANG Lihui

CHEN Qian

崔应麟

ZHU Lihong

PAN Junjie

Related Institution

The Second Clinical Medical College，Henan University of Chinese Medicine

Henan Provincial Hospital of Traditional Chinese Medicine/The Second Affiliated Hospital of Henan University of Chinese Medicine

Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University

Dingqiao Hospital of Hangzhou

西安市中医医院

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰

SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis

DOI：10.13288/j.11-2166/r.2025.16.004

摘要

Abstract

关键词

Keywords

references