Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach <italic style="font-style: italic">Qi</italic> Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial

HE Peishan; YANG Gongbo; JIANG Min; YAN Guojun; AN Songlin; JI Zhonghe; PAN Guofeng

doi:10.13288/j.11-2166/r.2025.18.009

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Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach Qi Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial

更新时间：2025-09-12

- Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach Qi Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial
- Journal of Traditional Chinese Medicine Vol. 66, Issue 18, Pages: 1902-1907(2025)
- 作者机构：
  
  1.首都医科大学附属北京世纪坛医院，北京市海淀区羊坊店铁医路10号，100038
  2.中国中医科学院西苑医院
  3.清华大学附属北京清华长庚医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.18.009
  CLC：
- Received：01 April 2025，
  
  Revised：2025-07-03，
  
  Published：17 September 2025
- 稿件说明：
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何佩珊,杨公博,姜敏等.远端取穴针刺防治腹膜假黏液瘤肿瘤细胞减灭术后脾胃气虚证患者胃肠功能紊乱的随机对照试验[J].中医杂志,2025,66(18):1902-1907.

HE Peishan,YANG Gongbo,JIANG Min,et al.Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach Qi Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial[J].Journal of Traditional Chinese Medicine,2025,66(18):1902-1907.
何佩珊,杨公博,姜敏等.远端取穴针刺防治腹膜假黏液瘤肿瘤细胞减灭术后脾胃气虚证患者胃肠功能紊乱的随机对照试验[J].中医杂志,2025,66(18):1902-1907. DOI： 10.13288/j.11-2166/r.2025.18.009.

HE Peishan,YANG Gongbo,JIANG Min,et al.Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach Qi Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial[J].Journal of Traditional Chinese Medicine,2025,66(18):1902-1907. DOI： 10.13288/j.11-2166/r.2025.18.009.

摘要

目的

观察远端取穴针刺疗法防治腹膜假黏液瘤患者肿瘤细胞减灭后胃肠功能紊乱的临床疗效。

方法

收集腹膜假黏液瘤行肿瘤细胞减灭术后脾胃气虚证患者88例，随机分为针刺组及对照组各44例。两组患者均给予西医围手术期常规治疗，从术后第2天开始针刺组同时给予远端取穴针刺治疗，对照组同时给予假穴浅刺，两组均每周治疗3次，隔日进行，疗程为14天。比较两组首次自主排便时间、拔除胃管时间及术后第3、7天胃管引流量；比较两组术后第7、14、21天时主要中医症状（恶心呕吐、体倦乏力）评分及腹胀分级评分；术前及术后第7、14、21天时综合医院焦虑抑郁量表评分及营养状态评分。

结果

针刺组首次自主排便时间及拔除胃管时间均比对照组短（

＜0.05），术后第7天针刺组胃管引流量较对照组少（

＜0.05）。术后第7天、第14天针刺组恶心呕吐、腹胀分级评分低于对照组，术后第14天、21天针刺组体倦乏力评分低于对照组（

＜0.05）。与本组术前比较，针刺组术后第14天、21天焦虑亚量表评分均降低（

＜0.05或

＜0.01）。术后第7天、14天针刺组焦虑亚量表评分均低于对照组（

＜0.05或

＜0.01）。针刺组术后第7天抑郁亚量表评分较术前升高（

＜0.05），而术后第14天、21天抑郁亚量表评分均较术前降低（

＜0.05和

＜0.01）。术后第14天针刺组抑郁亚量表评分低于对照组（

＜0.05）。针刺组术后第7天、14天营养状态评分较术前降低（

＜0.01），术后第14天针刺组营养状态评分高于对照组（

＜0.05）。

结论

远端取穴针刺疗法可以缩短腹膜假黏液瘤术后脾胃气虚证患者自主排便时间及拔除胃管时间，减少术后胃管引流量，改善术后恶心呕吐、体倦乏力、腹胀症状，促进术后胃肠功能恢复。

Abstract

Objective

To observe the clinical effect of distal acupoint acupuncture in treating gastrointestinal dysfunction in pseudomyxoma peritonei （PMP） patients after cytoreductive surgery with spleen-stomach

deficiency syndrome.

Methods

A total of 88 PMP patients with spleen-stomach

deficiency syndrome following cytoreductive surgery were randomized divided into an acupuncture group and a control group， each comprising 44 patients. Both

groups received standard Western perioperative care. Starting on the 2nd day after surgery， the acupuncture group received acupuncture selecting distal acupoints， while the control group received superficial non-acupoint sham acupuncture. Both groups received treatment on alternate days， three times weekly for a 14-day course. The following parameters were compared between groups， time to first spontaneous bowel movement， time to removal of nasogastric tube， and nasogastric tube drainage volume on days 3 and 7 after surgery； traditional Chinese medicine （TCM） symptoms scores of nausea/vomiting， fatigue， along with abdominal distension grading on days 7， 14， and 21 after surgery； and scores on Hospital Anxiety and Depression Scale （HADS） and nutritional status assessment at baseline and on day 7， 14， and 21 after surgery.

Results

The acupuncture group demonstrated shorter times of first spontaneous bowel movement and nasogastric tube removal compared to the control group （

＜0.05）. On day 7 after surgery， the acupuncture group exhibited lower nasogastric tube drainage volume than the control group （

＜0.05）. On days 7 and 14， the acupuncture group exhibited lower graded scores for nausea， vomiting， and abdominal distension compared to the control group. On day 14 and 21 after surgery， the acupuncture group also demonstrated lower fatigue scores than the control group （

＜0.05）. Compared with levels before surgery， the anxiety subscale scores in the acupuncture group decreased significantly at both day 14 and 21 after surgery （

＜0.05 or

＜0.01）. At day 7 and 14 after surgery， the anxiety subscale scores in the acupuncture group were lower than those in the control group （

＜0.05 or

＜0.01）. The depression subscale scores in the acupuncture group increased at day 7 after surgery compared to levels before surgery （

＜0.05）， but decreased at both day 14 and 2

1 after surgery compared to levels before surgery （

＜0.05 and

＜0.01）. On day 14 after surgery， the acupuncture group's depression subscale score was lower than that of the control group （

＜0.05）. Nutritional status scores on day 7 and 14 after surgery in the acupuncture group decreased compared to levels before surgery （

＜0.01）， but were higher than those of the control group on day 14 after surgery （

＜0.05）.

Conclusion

Acupuncture by selecting distal acupoints could help postoperative PMP patients with spleen-stomach

deficiency syndrome shorten the time to spontaneous bowel movement and the duration of nasogastric tube retention， reduce the postoperative gastric tube drainage volume， improve symptoms such as nausea， vomiting， fatigue， and abdominal distension， and promotes the recovery of gastrointestinal function.

关键词

Keywords

references

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Distal Acupoint Acupuncture for Treating Gastrointestinal Dysfunction in Pseudomyxoma Peritonei Patients with Spleen-Stomach Qi Deficiency Syndrome after Cytoreductive Surgery：A Randomized Controlled Trial

DOI：10.13288/j.11-2166/r.2025.18.009

摘要

Abstract

关键词

Keywords

references