DENG Kaiyuan,XU Zhifang,GUO Yi."Hand-Body Correlation" Mechanism Based on Traditional Chinese Medicine Theory and Modern Life Sciences[J].Journal of Traditional Chinese Medicine,2025,66(20):2082-2087.
DENG Kaiyuan,XU Zhifang,GUO Yi."Hand-Body Correlation" Mechanism Based on Traditional Chinese Medicine Theory and Modern Life Sciences[J].Journal of Traditional Chinese Medicine,2025,66(20):2082-2087.DOI: 10.13288/j.11-2166/r.2025.20.002.
"Hand-Body Correlation" Mechanism Based on Traditional Chinese Medicine Theory and Modern Life Sciences
The hand not only has sensory and motor functions, but also regulates the body by participating in neuroendocrine and immune regulation. In traditional Chinese external treatment methods such as acupuncture, moxibustion, bloodpricking, and massage all achieve therapeutic effects by stimulating specific parts of the hand. From the perspectives of traditional Chinese medicine and modern life sciences, this paper explored the pathways and regulatory mechanisms of hand stimulation in activating local microenvironment changes encompassing aspects of traditional Chinese medicine theory, clinical practice, and neuroendocrine-immune regulatory mechanisms, thereby participating in neuroendocrine immune regulation and ultimately achieving body regulation, with the aim of providing references for clinical practice in traditional Chinese medicine.
RANZANI R , LAMBERCY O , METZGER JC , et al . Neurocognitive robot-assisted rehabilitation of hand function: a randomized control trial on motor recovery in subacute stroke [J]. J Neuroeng Rehabil , 2020 , 24 ( 1 ): 115 .
HONG Y , HAY DL , QUIRION R , et al . The pharmaco-logy of adrenomedullin 2/intermedin [J]. Br J Pharmacol , 2012 , 166 ( 1 ): 110 - 120 .
TAKAYAMA S , SEKI T , WATANABE M , et al . The effect of warming of the abdomen and of herbal medicine on superior mesenteric artery blood flow:a pilot study [J]. Forsch Komplementmed , 2010 , 17 ( 4 ): 195 - 201 .
PEARSON J , LOW DA , STOHR E , et al . Hemodyna-mic responses to heat stress in the resting and exercising human leg: insight into the effect of temperature on skeletal muscle blood flow [J]. Am J Physiol Regul Integr Comp Physiol , 2011 , 300 ( 3 ): R663 - R673 .
KELLOGG DL JR , ZHAO JL , WU Y , et al . VIF/PACAP receptor me-diation of cutaneous active vasodilation during heat stress in humans [J]. J Appt Physiol (1985), 2010 , 109 ( 1 ): 95 - 100 .
YU N , WANG Z , CHEN Y , et al . The ameliorative effect of bloodletting puncture at hand twelve Jing-well points on cerebral edema induced by permanent middle cerebral ischemia via protecting the tight junctions of the blood-brain barrier [J]. BMC Complement Altern Med , 2017 , 17 ( 1 ): 470 .
LIU BH , ZHOU D , GUO Y , et al . Bloodletting puncture at hand twelve Jing-well points relieves brain edema after severe traumatic brain injury in rats via inhibiting MAPK signaling pathway [J]. Chin J Integr Med , 2021 , 27 ( 4 ): 291 - 299 .
YU NN , XU ZF , GAO Y , et al . Wake-promoting effect of bloodletting puncture at hand twelve Jing-well points in acute stroke patients: a multi-center randomized controlled trial [J]. Chin J Integr Med , 2021 , 27 ( 8 ): 570 - 577 .
ROOSTERMAN D , GOERGE T , SCHNEIDER SW , et al . Neuronal control of skin function: the skin as a neuroimmunoendocrine organ [J]. Physiol Rev , 2006 , 86 ( 4 ): 1309 - 1379 .