The Impact of "Two Reconstructions" Theoretical Framework on Improving the Clinical Efficacy of Traditional Chinese Medicine

HU Dongsen; ZHAO Linhua; XIE Pengfei; TANG Rumeng; HANG Xing; ZHOU Ling; ZHANG Xiangyuan; ZHANG Lili

doi:10.13288/j.11-2166/r.2025.23.001

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The Impact of "Two Reconstructions" Theoretical Framework on Improving the Clinical Efficacy of Traditional Chinese Medicine

更新时间：2025-12-04

- The Impact of "Two Reconstructions" Theoretical Framework on Improving the Clinical Efficacy of Traditional Chinese Medicine
- Journal of Traditional Chinese Medicine Vol. 66, Issue 23, Pages: 2401-2405(2025)
- 作者机构：
  
  1.北京中医药大学，北京市朝阳区北三环东路11号，100029
  2.中国中医科学院广安门医院
  3.成都中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.23.001
  CLC：
- Received：05 September 2025，
  
  Revised：2025-10-02，
  
  Published：02 December 2025
- 稿件说明：
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胡东森,赵林华,谢鹏飞等.“两个重构”理论框架对提高中医临床疗效的作用[J].中医杂志,2025,66(23):2401-2405.

HU Dongsen,ZHAO Linhua,XIE Pengfei,et al.The Impact of "Two Reconstructions" Theoretical Framework on Improving the Clinical Efficacy of Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2025,66(23):2401-2405.
胡东森,赵林华,谢鹏飞等.“两个重构”理论框架对提高中医临床疗效的作用[J].中医杂志,2025,66(23):2401-2405. DOI： 10.13288/j.11-2166/r.2025.23.001.

HU Dongsen,ZHAO Linhua,XIE Pengfei,et al.The Impact of "Two Reconstructions" Theoretical Framework on Improving the Clinical Efficacy of Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2025,66(23):2401-2405. DOI： 10.13288/j.11-2166/r.2025.23.001.

摘要

“两个重构”理论框架通过重构中西医结合诊疗体系，建立“分类-分期-分证”标准路径，提高了疾病识别精度和全程干预能力；通过重构现代本草体系，创新性融合中药传统功效与现代药理作用，形成“态靶同调”精准用药模式，并构建方药量效理论体系，增强了干预的靶向性和剂量精确性。“两个重构”理论框架是提高临床疗效的关键，其能够实现态、靶精准锁定与定向干预；可前移防治关口，贯通疾病全周期管理；助力构建标准化诊疗范式，确保疗效稳定、可重复、可评估；突破辨证局限，推动中医药诊疗领域的拓展。“两个重构”理论框架是推动中医药创新的系统路径，可为推动中西医结合高质量发展提供参考。

Abstract

By reconstructing the integrated Chinese and western medicine diagnostic and treatment system， the "Two Reconstructions" theoretical framework establishes a standardized pathway of "classification-staging-syndrome differentiation"， which improves the accuracy of disease identification and strengthens the capacity for full-course intervention； in addition， by reconstructing the modern materia medica system， it innovatively integrates the traditional properties and efficacy of Chinese herbal medicinals with modern pharmacological mechanisms， forming a "state-target co-regulation" precise medication model， and builds a dose-effect theoretical system for prescriptions and medicinals， thereby enhancing both the targeting accuracy and dosage precision of therapeutic interventions. The

Two Reconstructions

theorecitcal framework is a key strategy for enhancing clinical efficacy. It can precisely identify "states" and "targets" for directed

intervention， shift the focus of prevention and treatment earlier to enable full-cycle management， establish standardized paradigms for reproducible and evaluable efficacy， and expand the scope of clinical practice to address conditions without typical syndromes and critical illnesses. As a systematic pathway for innovation in TCM， this theoretical framework provides valuable insights and references for promoting the high-quality development of integrative Chinese and western medicine.

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references

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