Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient <italic style="font-style: italic">Qi</italic> Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'

FAN Yipin; LI Jianpeng; ZHANG Yingying

doi:10.13288/j.11-2166/r.2025.23.003

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Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient Qi Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'

更新时间：2025-12-04

- Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient Qi Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'
- Journal of Traditional Chinese Medicine Vol. 66, Issue 23, Pages: 2411-2415(2025)
- 作者机构：
  
  1.中国中医科学院中医临床基础医学研究所，北京市东城区东直门内南小街16号，100700
  2.北京中医药大学东直门医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2025.23.003
  CLC：
- Received：06 June 2025，
  
  Revised：2025-08-24，
  
  Published：02 December 2025
- 稿件说明：
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范逸品,李建鹏,张莹莹等.王永炎从虚气留滞、毒损脑络论治血管性认知障碍经验[J].中医杂志,2025,66(23):2411-2415.

FAN Yipin,LI Jianpeng,ZHANG Yingying.Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient Qi Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'[J].Journal of Traditional Chinese Medicine,2025,66(23):2411-2415.
范逸品,李建鹏,张莹莹等.王永炎从虚气留滞、毒损脑络论治血管性认知障碍经验[J].中医杂志,2025,66(23):2411-2415. DOI： 10.13288/j.11-2166/r.2025.23.003.

FAN Yipin,LI Jianpeng,ZHANG Yingying.Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient Qi Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'[J].Journal of Traditional Chinese Medicine,2025,66(23):2411-2415. DOI： 10.13288/j.11-2166/r.2025.23.003.

摘要

总结王永炎教授辨治血管性认知障碍（VCI）的经验。认为本病核心病因病机为虚气留滞、毒损脑络，以精气亏虚、脑络失养为本，痰、浊、瘀、热阻滞脑络为标，揭示了VCI因虚致滞、气滞成实、毒邪内生、络脉损伤的关键病机。以补虚行滞、解毒通络为总体治疗原则，以“养、通、清”三法为核心治法。临床中根据平台期、波动期、下滑期的不同特点，分别采用益气养血、补肾填精，宣通三焦、活血通络，清热解毒、豁痰降浊的治法，为中医临床治疗VCI提供指导。

Abstract

This paper summarized the experience of professor WANG Yongyan in differentiating and treating vascular cognitive impairment （VCI）. It is believed that the core etiology and pathogenesis of VCI are deficient

retention and stagnation， and toxin damaging brain collaterals. The essence lies in depletion of essence and

， and malnutrition of brain collaterals as the root cause， while phlegm， turbidity， stasis， and heat blocking brain collaterals act as the branch aspects. It reveals t

he pathogenesis essence of VCI as stagnation caused by deficiency and

stagnation transforming into excess， internal generation of toxin and collateral injury. The overall therapeutic principle is to tonify deficiency， move stagnation， resolve toxin， and unblock the collaterals， guided by the three core treatment methods of nourishing， unblocking， and clearing. Clinically， according to the different characteristics of the plateau phase， fluctuation phase， and decline phase， treatment methods including replenishing

and blood， tonifying the kidney and supplementing essence； promoting

sanjiao

（三焦） circulation and activating blood to dredge collaterals； clearing heat and resolving toxin， eliminating phlegm and reducing turbidity are respectively adopted. This provides clinical guidance for the treatment of VCI in traditional Chinese medicine.

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references

BADJI A ， YOUWAKIM J ， COOPER A ， et al . Vascular cognitive impaiment： past， present， and future challenges ［J］. Ageing Res Rev ， 2023 ， 90 ： 102042 . doi： 10.1016/j.arr.2023.102042 http://dx.doi.org/10.1016/j.arr.2023.102042 .

王伊龙，陈玮琪，叶瑾怡，等 . 脑小血管病：回眸2022 ［J］. 中国卒中杂志， 2023 ， 18 （ 1 ）： 17 - 41 .

中国卒中学会血管性认知障碍分会 . 中国血管性认知障碍诊治指南（2024版）［J］. 中华医学杂志， 2024 ， 104 （ 31 ）： 2881 - 2894 .

杨卉，蒋苏，赵峰，等 . 脑小血管病认知障碍的药物治疗研究进展［J］. 药学与临床研究， 2024 ， 32 （ 3 ）： 249 - 253 .

周小炫，黄俊山，谢敏，等 . 中医治未病：血管性轻度认知障碍专家共识［J］. 中国中医药信息杂志， 2020 ， 27 （ 3 ）： 1 - 5 .

范欣，罗乐，刘莹，等 . 中医药干预不同类型认知障碍的研究进展［J］. 现代中医药， 2025 ， 45 （ 2 ）： 54 - 60 .

陈昱彤，喻嵘，谭艳，等 . 血管性认知障碍的中医证型、证素分布及用药规律［J］. 湖南中医药大学学报， 2021 ， 41 （ 6 ）： 869 - 874 .

黄世敬，王永炎 . 缺血性脑白质病变“虚气留滞”病机探讨［J］. 北京中医药大学学报， 2011 ， 34 （ 8 ）： 513 - 516 .

徐世军，赵宜军，张文生，等 . 从中医脑络功能演变谈轻度认知障碍的病机［J］. 中医杂志， 2011 ， 52 （ 19 ）： 1627 - 1629 .

程安琪，刘彩燕，徐蔚海 . 血管性认知障碍的神经心理学和影像学表现研究进展［J］. 中国卒中杂志， 2023 ， 18 （ 11 ）： 1222 - 1227，1221 .

屈正，朱丹 . 血管性认知障碍发病机制［J］. 中国老年学杂志， 2020 ， 40 （ 4 ）： 892 - 896 .

李澎涛，王永炎，黄启福 . “毒损脑络”病机假说的形成及其理论与实践意义［J］. 北京中医药大学学报， 2001 ， 24 （ 1 ）： 1 - 6，16 .

高颖，谢颖桢，王永炎．试论浊毒在血管性痴呆发病中的作用［J］．中国中医急症， 2000 ， 9 （ 6 ）： 266 - 267 ．

刘艳，董新刚，王晓元，等 . 线粒体自噬与血管性认知障碍的相关性研究进展［J］. 协和医学杂志， 2025 ， 16 （ 2 ）： 338 - 349 .

张允岭，梅建勋，谢颖桢，等 . 老年期血管性痴呆分期分证探讨［J］. 中医杂志， 2008 ， 49 （ 2 ）： 173 - 175 .

FOLSTEIN MF ， FOLSTEIN SE ， MCHUGH PR . " Mini-mental state". A practical method for grading the cognitive state of patients for the clinician ［J］. J Psychiatr Res ， 1975 ， 12 （ 3 ）： 189 - 198 .

田金洲 . 王永炎院士查房实录［M］. 北京：人民卫生出版社， 2015 ： 88 .

谢颖桢 . 王永炎院士神经内科病证实验录［M］. 北京：中国中医药出版社， 2018 .

邹忆怀，谢颖桢，高颖，等 . 聪圣胶囊治疗血管性痴呆30例临床研究［J］. 北京中医药大学学报， 2001 ， 24 （ 6 ）： 54 - 57 .

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Related Institution

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Experience of WANG Yongyan in Treating Vascular Cognitive Impairment from the Perspectives of 'Deficient Qi Retention and Stagnation' and 'Toxin Damaging Brain Collaterals'

DOI：10.13288/j.11-2166/r.2025.23.003

摘要

Abstract

关键词

Keywords

references