Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"

WANG Yong; CHENG Zixuan; KONG Weiyang; SUN Yuwei; SHI Yunxuan; QIN Ruyu; LIU Zhaidong

doi:10.13288/j.11-2166/r.2026.01.005

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Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"

更新时间：2026-01-15

- Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"
- Journal of Traditional Chinese Medicine Vol. 67, Issue 1, Pages: 26-30(2026)
- 作者机构：
  
  1.山东中医药大学第一临床医学院，山东省济南市历下区经十路16369号，250355
  2.山东中医药大学附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.01.005
  CLC：
- Received：08 September 2025，
  
  Revised：2025-10-22，
  
  Published：02 January 2026
- 稿件说明：
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王墉,程梓轩,孔维扬等.基于“甘守津还”探讨恶性肿瘤高凝状态的病机与防治[J].中医杂志,2026,67(01):26-30.

WANG Yong,CHENG Zixuan,KONG Weiyang,et al.Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"[J].Journal of Traditional Chinese Medicine,2026,67(01):26-30.
王墉,程梓轩,孔维扬等.基于“甘守津还”探讨恶性肿瘤高凝状态的病机与防治[J].中医杂志,2026,67(01):26-30. DOI： 10.13288/j.11-2166/r.2026.01.005.

WANG Yong,CHENG Zixuan,KONG Weiyang,et al.Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"[J].Journal of Traditional Chinese Medicine,2026,67(01):26-30. DOI： 10.13288/j.11-2166/r.2026.01.005.

摘要

基于“甘守津还”提出恶性肿瘤高凝状态的核心病机为气虚津亏、血脉瘀滞，病机演变遵循“气虚→津亏→血瘀”的动态规律。据此确立顾护中焦、复津行血为治则的分阶段论治体系：初期健脾益气以生津，对应中焦虚损、津亏之始；中期滋阴通络以通津，针对津失输布、内燥伤络；晚期固阴化瘀以守津，化解阴伤液耗、瘀毒互结。通过调节津液代谢以改善高凝状态，以期为中医药防治本病提供思路。

Abstract

Based on the theory of "sweet-flavored medicinals retaining and restoring body fluid"， this paper proposed that the core pathogenesis of hypercoagulable state in malignant tumors is

deficiency and fluid consumption， blood stasis and vessels stagnation， which evolves dynamically according to the pattern "

deficiency → fluid consumption → blood stasis". Accordingly， a staged treatment system is established with the general principle of "fortifying the middle

jiao

， restoring fluid and activating blood circulation". In the initial stage， invigorating the spleen and boosting

to generate body fluid， targeting the onset of middle

jiao

deficiency and body fluid consumption； in the middle stage， nourishing

yin

and unblocking collaterals to facilitate body fluid circulation， addressing the disorder of body fluid transportation and collateral injury caused by internal dryness； in the late stage， consolidating

yin

and resolving blood stasis to retain body fluid， resolving

yin

impairment， fluid exhaustion， and binding of stasis and toxin. By regulating body fluid metabolism to improve the hypercoagulable state， this system is intended to provide insights for the prevention and treatment of hypercoagulable state in malignant tumors with traditional Chinese medicine.

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references

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