Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in <italic style="font-style: italic">The</italic> <italic style="font-style: italic">Inner Canon of Yellow Emperor</italic> （《黄帝内经》）

ZHU Jinbiao; YUAN Mengyun; BAI Lu; NIE Duorui; WU Mianhua; YAN Yingjie; DING Dawei

doi:10.13288/j.11-2166/r.2026.05.017

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Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in The Inner Canon of Yellow Emperor （《黄帝内经》）

更新时间：2026-05-19

- Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in The Inner Canon of Yellow Emperor （《黄帝内经》）
- Journal of Traditional Chinese Medicine Vol. 67, Issue 5, Pages: 575-579(2026)
- 作者机构：
  
  1.江苏省中医院，江苏省南京市秦淮区汉中路155号，210029
  2.南京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.05.017
  CLC：
- Received：27 August 2025，
  
  Revised：2025-10-28，
  
  Published：02 March 2026
- 稿件说明：
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祝金标,袁梦云,白璐等.从《黄帝内经》血枯病探讨肿瘤厌食-恶病质综合征的病机及辨治思路[J].中医杂志,2026,67(05):575-579.

ZHU Jinbiao, YUAN Mengyun, BAI Lu, et al. Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in The Inner Canon of Yellow Emperor （《黄帝内经》）[J]. Journal of Traditional Chinese Medicine, 2026, 67(5): 575-579. DOI: 10.13288/j.11-2166/r.2026.05.017.
祝金标,袁梦云,白璐等.从《黄帝内经》血枯病探讨肿瘤厌食-恶病质综合征的病机及辨治思路[J].中医杂志,2026,67(05):575-579. DOI： 10.13288/j.11-2166/r.2026.05.017.

ZHU Jinbiao, YUAN Mengyun, BAI Lu, et al. Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in The Inner Canon of Yellow Emperor （《黄帝内经》）[J]. Journal of Traditional Chinese Medicine, 2026, 67(5): 575-579. DOI: 10.13288/j.11-2166/r.2026.05.017. DOI：

摘要

以《黄帝内经》血枯病为指导，提出肿瘤厌食-恶病质综合征的三期辨治思路，即癌因性厌食期病机为癌伐脾胃、中焦滞运，治以健脾开胃、消积助运，选用《先醒斋医学广笔记》之资生丸或《医学衷中参西录》之资生汤加减治疗；营养不良恶病质前期病机为血气失养、精亏不生，治以养血和营、温阳益气，选用黄芪建中汤加减治疗；恶病质期病机为血虚精枯、瘀血阻络，治以补虚填精、通络祛瘀，选用补中益气汤合左归饮加减治疗。

Abstract

Based on the concept of "blood exhaustion" from

The

Inner Canon of Yellow Emperor

（《黄帝内经》）， a three-stage syndrome differentiation and treatment strategy for cancer-related anorexia-cachexia syndrome is proposeed. In the cancer-induced anorexia stage， the pathogenesis is charact

erized by cancer consuming the spleen and stomach， leading to stagnation of transportation and transformation in the middle

jiao

（焦）. Treatment should focus on strengthening the spleen， promoting appetite， dispersing accumulation， and aiding digestion， with modified

Zisheng Pills

（资生丸） in

Extensive Notes on Medicine from Xian Xing Studio

（《先醒斋医学广笔记》） or

Zisheng Decoction

（资生汤） in

Records of Chinese Medicine with Reference to Western Medicine

（《医学衷中参西录》）. In the pre-cachectic stage of malnutrition， the pathogenesis involves insufficient nourishment of blood and

with essence depletion hindering production. Treatment should focus on nourishing blood and harmonizing

ying

（营）， warming

yang

and supplementing

， and modified

Huangqi Jianzhong Decoction

（黄芪建中汤） can be used. In the cachectic stage， the pathogenesis involves blood deficiency and essence exhaustion， with blood stasis obstructing the collaterals. The therapeutic approach should focus on tonifying deficiency and replenishing essence， unblocking collaterals， and removing stasis， and modified

Buzhong Yiqi Decoction

（补中益气汤） and

Zuo Gui Beverage

（左归饮） are suggested.

关键词

Keywords

references

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Pathogenesis and Treatment Approach of Cancer-Related Anorexia-Cachexia Syndrome Based on the Concept of "Blood Exhaustion" in The Inner Canon of Yellow Emperor （《黄帝内经》）

DOI：10.13288/j.11-2166/r.2026.05.017

摘要

Abstract

关键词

Keywords

references