HU Shengjuan,HOU Li,SUN Tao,et al.Differentiation and Treatment of Small Cell Lung Cancer from the Perspective of "Internal Wind in Hidden Circulation"[J].Journal of Traditional Chinese Medicine,2026,67(09):1003-1007.
HU Shengjuan,HOU Li,SUN Tao,et al.Differentiation and Treatment of Small Cell Lung Cancer from the Perspective of "Internal Wind in Hidden Circulation"[J].Journal of Traditional Chinese Medicine,2026,67(09):1003-1007.DOI: 10.13288/j.11-2166/r.2026.09.013.
Differentiation and Treatment of Small Cell Lung Cancer from the Perspective of "Internal Wind in Hidden Circulation"
Small cell lung cancer (SCLC) is characterized by rapid onset, high invasiveness, and a strong tendency for recurrence and metastasis, which aligns with the pathogenic characteristics of wind pathogen in traditional Chinese medicine (TCM). This paper explores the pathological mechanism and dynamic pattern identification and treatment of SCLC from the perspective of "internal wind in hidden circulation". It is proposed that the core pathogenesis of SCLC is rooted in depletion of healthy
qi
, with binding of phlegm,
stasis, and toxin. When pathogenic factors become excessive, the ascending and descending of
yang qi
becomes disordered, transforming into wind. This leads to internal wind in hidden circulation, which moves erratically and damages healthy
qi
. In the limited stage, cancer toxin accumulates and internal wind arises covertly, treatment for which should focus on regulating
qi
and resolving toxin, defending against wind and resisting pathogen with modified
Bufei Decoction
(补肺汤) and
Shengjiang Powder
(升降散). In the early extensive stage, phlegm and stasis generate wind, and internal wind spreads through collate-rals; treatment should resolve phlegm and dispel stasis, extinguish wind and resolve toxin, with modified
Lingjiao Gouteng Decoction
(羚角钩藤汤) combined with
Tianma Gouteng Beverage
(天麻钩藤饮). During the treatment stage, there is
qi
and
yin
depletion, and deficient wind harassing the interior, for which it is recommended to boost
qi
and nourish
yin
, soften the liver and extinguish wind, with modified
Zhengan Xifeng Decoction
(镇肝熄风汤) combined with
Qingzao Jiufei Decoction
(清燥救肺汤). In the progression stage, internal wind stirs again and cancer toxin scurries; treatment should focus on strengthening the healthy
qi
and replenishing essence, restraining wind and penetrating toxin, with modified
Sanjia Fumai Decoction
(三甲复脉汤). In the terminal stage,
yin
and
yang
are on the verge of dissociation and depleted
yang
floats upward; treatment should constrain and astringe to prevent collapse, rescue
yang
and contain
yin
, with modified
Dihuang Drink
(地黄饮子) combined with
Laifu Decoction
(来复汤).
关键词
Keywords
references
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