Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen

DAI Xinyi; ZHANG Jiaqi; SHE Meiling; TANG Xudong

doi:10.13288/j.11-2166/r.2026.11.016

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Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen

更新时间：2026-05-29

- Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen
- Journal of Traditional Chinese Medicine Vol. 67, Issue 11, Pages: 1231-1234(2026)
- 作者机构：
  
  中国中医科学院西苑医院脾胃病研究所，北京市海淀区西苑操场1号，100091
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.11.016
  CLC：
- Received：12 September 2025，
  
  Revised：2026-02-20，
  
  Accepted：28 January 2026，
  
  Published：02 June 2026
- 稿件说明：
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戴心怡,张佳琪,佘美龄等.从湿热伏邪角度防治溃疡性结肠炎复发[J].中医杂志,2026,67(11):1231-1234.

DAI Xinyi,ZHANG Jiaqi,SHE Meiling,et al.Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen[J].Journal of Traditional Chinese Medicine,2026,67(11):1231-1234.
戴心怡,张佳琪,佘美龄等.从湿热伏邪角度防治溃疡性结肠炎复发[J].中医杂志,2026,67(11):1231-1234. DOI： 10.13288/j.11-2166/r.2026.11.016.

DAI Xinyi,ZHANG Jiaqi,SHE Meiling,et al.Prevention and Treatment of the Relapse of Ulcerative Colitis Based on the Theory of Damp-Heat Latent Pathogen[J].Journal of Traditional Chinese Medicine,2026,67(11):1231-1234. DOI： 10.13288/j.11-2166/r.2026.11.016.

摘要

认为溃疡性结肠炎（UC）的复发契合伏邪“潜伏隐匿、伺机而发”的动态特征。结合伏邪理论，提出湿热伏邪潜伏于内，日久由气入血，致气血失调、肠络受损，是UC复发的病机核心。并据此进行分期治疗，活动期治以清化湿热、行气调血，以葛根芩连汤为基础方加减；缓解期治以扶正透邪、调补脾肾，以自拟健脾清肠合剂加减，为其临床治疗提供参考。

Abstract

Aligning with the ulcerative colitis （UC） dynamic characteristics of latent pathogens， that is "remaining latent and concealed， and manifesting when triggered"， and following the latent pathogen theory， it is proposed that the core pathogenesis of UC recurrence is latent damp-heat pathogen concealed internally， progressing from

to blood level over time， and leading to

-blood disharmony and intestinal collateral damage. Accordingly， stage-based treatment is recommended. During the active stage， it is suggested to clear damp-heat， move

， and regulate blood using modified

Gegen Qinlian Decoction

（葛根芩连汤）. During the remission stage， the treatment should focus on reinforcing healthy

and venting pathogen， regulate and tonify the spleen and kidney with a self-made

Jianpi Qingchang Mixture

（健脾清肠合剂）. These approaches may provide a reference for the clinical treatment of UC.

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references

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Related Institution

School of Basic Medical Sciences，Chengdu University of Traditional Chinese Medicine

Dongfang Hospital，Beijing University of Chinese Medicine

School of Traditional Chinese Medicine，Beijing University of Chinese Medicine

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Japan Friendship Hospital/ National Center for Integrated Traditional Chinese and Western Medicine

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