WANG Guibin,LIN Sijie,LIU Zihan,et al.Modern Expanded Application of Ancient Classic Formulae from the Perspective of Syndrome‑Formula Ontology Reconstruction[J].Journal of Traditional Chinese Medicine,2026,67(12):1251-1257.
WANG Guibin,LIN Sijie,LIU Zihan,et al.Modern Expanded Application of Ancient Classic Formulae from the Perspective of Syndrome‑Formula Ontology Reconstruction[J].Journal of Traditional Chinese Medicine,2026,67(12):1251-1257.DOI: 10.13288/j.11-2166/r.2026.12.002.
Modern Expanded Application of Ancient Classic Formulae from the Perspective of Syndrome‑Formula Ontology Reconstruction
As the core carrier of the inheritance and innovation of traditional Chinese medicine (TCM), the modern expanded application of classic formulae is an inevitable trend for TCM to adapt to the changes in disease spectrum and achieve academic development. However, several challenges remain, including the vague definition of syndrome-formula ontology between ancient and modern times, the insufficient adaptability of the evidence grading system, and the disconnection between theory and clinical practice, having severely restricted the precise application and standardized development of classic formulae. Based on the current status of the modern expanded application of classic formulae, and grounded in the core theory of formula-syndrome correspondence in TCM, this paper constructs a theoretical framework of "syndrome-formula ontology reconstruction". The framework systematically expounds its core connotations, theoretical foundations and practical logic, and further clarifies the reconstruction direction of the TCM-specific evidence grading system by taking correspondence between formula and syndrome as the core, constructing a multi-dimensional and integrated evaluation framework, and adhering to the orientation of clinical application. The ultimate goal is to form a theoretical paradigm characterized by "syndrome-formula ontology reconstruction-evidence grading reconstruction-precise clinical application", thereby providing theoretical support for the digital inheritance, evidence-based development, and modern application of classical prescriptions.
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