Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original <italic style="font-style: italic">Qi</italic> Theory

DING Yingge; CHEN Shilong; WANG Shurui; WANG Lihui; CHEN Qian

doi:10.13288/j.11-2166/r.2026.14.004

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Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory

更新时间：2026-07-17

- Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory
- Journal of Traditional Chinese Medicine Vol. 67, Issue 14, Pages: 1485-1490(2026)
- 作者机构：
  
  1.河南中医药大学第二临床医学院，河南省郑州市金水区东风路6号，450002
  2.河南省中医院/河南中医药大学第二附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.14.004
  CLC：
- Received：20 October 2025，
  
  Revised：2026-06-07，
  
  Accepted：16 January 2026，
  
  Online First：15 July 2026，
  
  Published：17 July 2026
- 稿件说明：
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丁英歌,陈世龙,王姝瑞等.崔应麟运用元气理论辨治儿童线粒体脑肌病经验[J].中医杂志,2026,67(14):1485-1490.

DING Yingge,CHEN Shilong,WANG Shurui,et al.Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory[J].Journal of Traditional Chinese Medicine,2026,67(14):1485-1490.
丁英歌,陈世龙,王姝瑞等.崔应麟运用元气理论辨治儿童线粒体脑肌病经验[J].中医杂志,2026,67(14):1485-1490. DOI： 10.13288/j.11-2166/r.2026.14.004.

DING Yingge,CHEN Shilong,WANG Shurui,et al.Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory[J].Journal of Traditional Chinese Medicine,2026,67(14):1485-1490. DOI： 10.13288/j.11-2166/r.2026.14.004.

摘要

总结崔应麟教授运用元气理论辨治儿童线粒体脑肌病的临证经验。认为儿童线粒体脑肌病以元气亏虚为核心病机，主张以固本培元为基本治则。临证将该病分为肾精不足、脾气虚弱、肝肾阴虚、元气郁滞兼痰瘀阻络四种证型，分别运用自拟固精益元汤以补肾填精、益气培元，益元汤加减以健脾益气、固本培元，大补元煎加减以滋补肝肾、补益元气，自拟化痰祛瘀方以益气活血、化痰通络。随证灵活用药，兼顾脏腑功能与气血阴阳平衡，可为儿童线粒体脑肌病的临证治疗提供思路。

Abstract

This paper summarizes Professor CUI Yinglin's clinical experience in treating pediatric mitochondrial encephalomyopathy based on the original

theory. It is proposed that original

depletion is the core pathogenesis， and the fundamental therapeutic principle is consolidating the root and replenishing original

. Clinically， the disease is classified into four syndrome types， including insufficiency of kidney essence， spleen

depletion， liver-kidney

yin

deficiency， and original

constraint and stagnation accompanied by phlegm-sta

sis obstructing the collaterals. Correspondingly， self-formulated

Gujing Yiyuan Decoction

（固精益元汤） can be used to tonify the kidney and replenish essence， reinforce and strengthen original

. Modified

Yiyuan Decoction

（益元汤） is used to fortify the spleen and supplement

， consolidate the root and replenish original

. Modified

Da Bu Yuan Decoction

（大补元煎） is employed to nourish the liver and kidney， and replenish original

. Self-formulated

Huatan Quyu Formula

（化痰祛瘀方） is used to supplement

and activating blood， resolve phlegm and unblocking the collaterals. Medication is flexibly adjusted according to syndrome differentiation， with simultaneous attention to the functional balance of the z

ang

（脏腑） organs and the harmony of

， blood，

yin

， and

yang

， which may provide useful guidance for the clinical treatment of pediatric mitochondrial encephalomyopathy.

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Keywords

references

Davison J E ， Rahman S . Recognition， investigation and management of mitochondrial disease ［J］. Arch Dis Child ， 2017 ， 102 （ 11 ）： 1082 - 1090 .

贾建平，陈生弟，崔丽英，等 . 神经病学［M］. 9版 . 北京：人民卫生出版社， 2016 ： 433 - 436 .

李军强，王天成 . 线粒体脑肌病的研究进展［J］. 癫痫杂志， 2021 ， 7 （ 5 ）： 440 - 444 .

刘珍珠，刘修超，佟常青，等 . 元气、原气、真气、正气的内涵及相互关系探析［J］. 中医杂志， 2022 ， 63 （ 5 ）： 401 - 406 .

Falkenberg M ， Larsson N G ， Gustafsson C M . Replication and transcription of human mitochondrial DNA ［J］. Annu Rev Biochem ， 2024 ， 93 （ 1 ）： 47 - 77 .

郭玉璞 . 线粒体脑肌病［J］. 中华神经科杂志， 1997 ， 30 （ 5 ）： 46 - 50 .

姚渊，李楠 . 基于系统生物学解析三焦辨证科学内涵［J］. 世界科学技术-中医药现代化， 2026 ， 28 （ 4 ）： 1176 - 1185 .

傅钰诗，赵吉超 . 基于网络药理学和分子对接探讨大补元煎治疗慢性疲劳综合征作用机制［J］. 中国中医药图书情报杂志， 2024 ， 48 （ 6 ）： 35 - 41 .

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Related Institution

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Wuxi Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine

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Clinical Experience of Professor CUI Yinglin in Treating Pediatric Mitochondrial Encephalomyopathy Based on the Original Qi Theory

DOI：10.13288/j.11-2166/r.2026.14.004

摘要

Abstract

关键词

Keywords

references