Construction of a Dual-dimensional Outcome System for Musculoskeletal Pain：A Common Core Outcome Set and A Specific Outcome Set for Traditional Chinese Medicine External Treatment

LIANG Yuanwen; CHEN Hong; SUN Yanan; YU Changhe

doi:10.13288/j.11-2166/r.2026.14.007

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Construction of a Dual-dimensional Outcome System for Musculoskeletal Pain：A Common Core Outcome Set and A Specific Outcome Set for Traditional Chinese Medicine External Treatment

更新时间：2026-07-17

- Construction of a Dual-dimensional Outcome System for Musculoskeletal Pain：A Common Core Outcome Set and A Specific Outcome Set for Traditional Chinese Medicine External Treatment
  增强出版
- Journal of Traditional Chinese Medicine Vol. 67, Issue 14, Pages: 1503-1508(2026)
- 作者机构：
  
  1.北京中医药大学第一临床医学院，北京市东城区海运仓5号，100700
  2.北京中医药大学东直门医院
  3.首都医科大学宣武医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.14.007
  CLC：
- Received：28 June 2025，
  
  Revised：2026-04-30，
  
  Accepted：01 September 2025，
  
  Online First：15 July 2026，
  
  Published：17 July 2026
- 稿件说明：
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梁元文,陈红,孙亚男等.肌肉骨骼疼痛共性核心集与中医外治特色集双维结局指标集的构建[J].中医杂志,2026,67(14):1503-1508.

LIANG Yuanwen,CHEN Hong,SUN Yanan,et al.Construction of a Dual-dimensional Outcome System for Musculoskeletal Pain：A Common Core Outcome Set and A Specific Outcome Set for Traditional Chinese Medicine External Treatment[J].Journal of Traditional Chinese Medicine,2026,67(14):1503-1508.
梁元文,陈红,孙亚男等.肌肉骨骼疼痛共性核心集与中医外治特色集双维结局指标集的构建[J].中医杂志,2026,67(14):1503-1508. DOI： 10.13288/j.11-2166/r.2026.14.007.

LIANG Yuanwen,CHEN Hong,SUN Yanan,et al.Construction of a Dual-dimensional Outcome System for Musculoskeletal Pain：A Common Core Outcome Set and A Specific Outcome Set for Traditional Chinese Medicine External Treatment[J].Journal of Traditional Chinese Medicine,2026,67(14):1503-1508. DOI： 10.13288/j.11-2166/r.2026.14.007.

摘要

目的

构建肌肉骨骼疼痛共性核心集（MKP-COS）与肌肉骨骼疼痛中医外治特色集（MKP-SOS-ETCM），为肌肉骨骼疼痛相关临床研究提供依据，也为相关领域核心结局指标集的构建提供参考。

方法

检索现有肌肉骨骼疼痛（MKP）核心结局指标集（COS）文献，提取核心结局指标作为条目池，通过德尔菲法邀请专家就肌肉骨骼疼痛共性结局指标和中医外治干预特色结局指标达成共识，共识纳入标准设定为重要性评分7~9分专家数≥75%。

结果

纳入47项COS研究，经讨论整理后初步条目池包含34个结局指标，经过3轮德尔菲专家共识，得出肌肉骨骼疼痛共性核心结局集包括疼痛、运动功能、关节活动度、日常生活活动能力、不良事件/不良反应5个结局指标；中医外治特色结局集包括僵硬（包括晨僵）、关节压痛计数、工作状态/生产力、医生整体评估、结构损伤、肌肉力量6个结局指标。

结论

构建了肌肉骨骼疼痛共性核心结局集及肌肉骨骼疼痛中医外治特色结局集，形成了疾病共性+干预特色的双维度评估体系。

Abstract

Objective

To develop a core outcome set for musculoskeletal pain （MKP-COS） and a specific outcome set for traditional Chinese medicine external treatment （MKP-SOS-ETCM）， providing a standardized basis for clinical research in musculoskeletal pain and serving as a reference for core outcome set （COS） development in related fields.

Methods

Existing COS studies on musculoskeletal pain （MKP） were systematically searched， and core outcome indicators were extracted to form an initial item pool. The Delphi method was used， in which experts were invited to reach consensus on MKP-COS and MKP-SOS-ETCM. The inclusion criteria for consensus are set as an importance score of 7-9 points with ≥75% of experts reaching agreement.

Results

A total of 47 COS studies were included， and after discussion and consolidation， a preliminary item pool containing 34 outcome indicators was established. After three rounds of Delphi expert consensus， MKP-COS was identified， including five outcomes including pain， motor function， joint range of motion， activities of daily living， and adverse events/ adverse reactions； MKP-SOS-ETCM included six outcomes involving stiffness （including morning stiffness）， joint tenderness count， work status/ productivity， overall physician assessment， structural damage， and muscle strength.

Conclusion

This study has established MKP-COS and MKP-SOS-ETCM， forming a dual-dimensional outcome assessment system integrating both disease commonality and intervention specificity.

关键词

Keywords

references

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