Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"

ZHENG Xiaoqing; LI Yifan; DING Ying; XU Shanshan; WANG Long; XING Yaping; XING Wenchao

doi:10.13288/j.11-2166/r.2026.15.016

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Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"

更新时间：2026-08-05

- Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"
- Journal of Traditional Chinese Medicine Vol. 67, Issue 15, Pages: 1673-1676(2026)
- 作者机构：
  
  1.河南中医药大学第一附属医院儿科医院，河南省郑州市金水区人民路19号，450000
  2.河南中医药大学儿科医学院
  3.天津中医药大学第一附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2026.15.016
  CLC：
- Received：10 January 2026，
  
  Revised：2026-06-01，
  
  Accepted：27 May 2026，
  
  Online First：03 August 2026，
  
  Published：02 August 2026
- 稿件说明：
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郑肖庆,李一凡,丁樱等.从热、瘀、虚探讨儿童IgA血管炎性肾炎的辨治[J].中医杂志,2026,67(15):1673-1676.

ZHENG Xiaoqing,LI Yifan,DING Ying,et al.Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"[J].Journal of Traditional Chinese Medicine,2026,67(15):1673-1676.
郑肖庆,李一凡,丁樱等.从热、瘀、虚探讨儿童IgA血管炎性肾炎的辨治[J].中医杂志,2026,67(15):1673-1676. DOI： 10.13288/j.11-2166/r.2026.15.016.

ZHENG Xiaoqing,LI Yifan,DING Ying,et al.Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"[J].Journal of Traditional Chinese Medicine,2026,67(15):1673-1676. DOI： 10.13288/j.11-2166/r.2026.15.016.

摘要

认为热、瘀、虚为儿童IgA血管炎性肾炎（IgAVN）病机核心，其中虚为发病之本，热为起病之标，瘀为迁延之根。基于此确立清热凉血、化瘀通络、扶正固本的总治则。以自拟清热止血方为基础方，并结合疾病不同病程特征，将本病凝练为血热瘀阻、气阴两虚、脾肾两虚三类核心证型，分型辨治。治疗全程兼顾化瘀通络、顾护小儿脾胃正气，为儿童IgAVN的中医诊疗提供思路。

Abstract

The core pathogenesis of childhood IgA vasculitis nephritis （IgAVN） lies in the intermingled conditions of heat， stasis and deficiency. Deficiency is the fundamental cause， while heat acts as the predominant manifestation at the initial stage， and stasis serves as the key factor leading to protracted illness. Based on this understanding， the overall therapeutic principle of clearing heat and cooling blood， dissolving stasis and unblocking collaterals， reinforcing healthy

and consolidating the root is established. A self-formulated

Qingre Zhixue Formula

（清热止血方） is used as the basic prescription. According to the characteristics of different disease stages， childhood IgAVN is further classified into three main syndrome types， including blood heat with stasis obstruction， deficiency of both

and

yin

， and deficiency of both spleen and kidney， with corresponding syndrome-based treatments. Throughout the treatment process， emphasis is placed on dissolving stasis and unblocking collaterals， while protecting the spleen and stomach of children and maintaining healthy

. This paper provides new perspectives for diagnosis and treatment of childhood IgAVN with traditional Chinese medicine.

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references

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