Galvanic skin reflex（GSR）of 230 pa- tients of different types of pathological syn- drome as diagnosed by traditional Chinese medicine is studied. As compared with that of normal persons and patients either of mixed type or of interio-deficient type but with heat syndrome

GSR of patients of interio- deficient type with cold syndrome are signi- ficantly depressed.After a period of therapy by traditional Chinese medicine to restore the vital energy

the vital Junction of"spleen"and "kidney"

the depressed GSR tends to be reactivated. correlated with other signs

we find that GSR is depressed in hypotension

visce- roptosis

edema of unknown origin patients and patients with low urinary 17-hydroxy corticosteroid excretion. This result suggests that in patients of interio-deficient type with cold syndrome the nervous activity and general physiologi- cal function may be in a depressed condi- tion.