A berbal drug

Inigo pulverata levis

therapeutically quite effective to chronic granulocytic leukemia has been isolated from the Chinese herbal medicine"Pilulae Ange- licae Sinensis et Aloes"by Ghengdu Tradi- tional Chinese Medical College

Institute of Hematology of the Chinese Academy of Me- dical Science and Institute of Chinese Ma- teria medica of Sichuan Province after se- veral years of cooperation.Its effective che- mical constituent"Indigo red or 4-Isatine

2-Indogenide"has subsequently been extra- cted thereafter. This paper reported the clinical results of Synthetic Indigo red in treatment of 16 cases of chronic granulocytic leukemia.All cases were effective

including 6 cases of com- plete remission

2 cases of partical remission and 8 cases of improvement.There was no marked damage to cardiac

hepatic and renal functions.Gastrointestinal reactions were sli- ght

usually endurable to the patients.Headache appeared in one case and subsided on discon- tinuance of treatment.Marked bleeding ten- dency occured in another case due to throm- bocytopenia.