Su Xianshi. Clinical Observation and Laboratory Investigation on 100 Cases of Chronic Viral Hepatitis Treated by“San-Cao(Three Kinds of Herb Plants)Decoction”[J]. Journal of Traditional Chinese Medicine1980, (4): 22-25.
Su Xianshi. Clinical Observation and Laboratory Investigation on 100 Cases of Chronic Viral Hepatitis Treated by“San-Cao(Three Kinds of Herb Plants)Decoction”[J]. Journal of Traditional Chinese Medicine1980, (4): 22-25.DOI: 10.13288/j.11-2166/r.1980.04.009.
三草汤治疗慢性病毒性肝炎100例的临床观察及实验研究
摘要
<正> 三草汤(夏枯草、白花蛇舌草、甘草)对急性黄疸型肝炎有较好的临床效果
动物实验证明它具有利胆作用
对四氯化碳引起的肝脏损害有明显的降酶作用
组织学和组织化学的观察表明它对肝脏有保护作用。为了进一步验证该方的疗效
一年来收治慢性肝炎100例进行临床观察
对该方的作用机理作进一步的研究。现将结果小结如下。
Abstract
This article deals with the clinical andexperimental research on active chronic he-patitis treated with syrup or injection compo-sed of Oldenlandia diffusa
Prunella vulgarisand Glycyrrhiza.100 cases
in which 40 treated with syrups and 60 with injections
received a course of treatment for 60 days
all showed satisfactory effectiveness in theimprovement of symptoms
reduction in thesize of the enlarged spleen and liver.As tohepatic function
suppression of GPT activityproved satisfactory.The total effective ratein the syrup group was 82.5% with 45%of marked effectiveness
while that of theinjection group was 90% and 43.3% respe-ctively.Concerning the HBsAg test
the syrupgroup was proved to be non-effective
whilethe injection group had a percentage of 38.3with negative HBsAg test.In the injectiongroup
24 cases were with positive HBeAgtest before treatment
and 15 cases of themturned to negative after treatment.By applying agglutinin absorption inhi-bition test
the author was able to find thatthe injection of these herbs contained mate-rial related to blood typing.Through thetests of EA
EAC
hemolytic plague
phago-cytic index etc
both in man and in animal
it was shown that the preparation was capa-ble of strenthening the immunity of orga-nisms.R-PHA
RIA methods were adoptedto observe the effect of the preparation
indifferent concentrations
on the activity ofHBsAg under various durations and tempe-ratures.Preparations in 1:8 dilution revealeddistinct inhibitory effect on HBsAg and thismight be one of the effective factors of theprescription in the treatment of chronic he-patitis.