50% injection of Radix Aconiti praepa-rata adminitered at 0.013 or 0.01 ml/gm.bd.wt.intraperitoneally can markedly improveanoxia-endurance in mice.In rats

acutemyocardial ischemia and arrhythmia inducedby pituitrin are significantly countered bythe injection at 5 mg/100 gm.bd.wt..Its modeof action is similar to that of nitroglycerine

but the latter does not possess antiarrhythmiceffect.Pituitrin-induced bradycardia andfirst stage（5—15 sec.）electrocardiographicchanges in rats are not affected by eitherinjection of Radix Aconiti praeparata or ni-troglycerine.