Inhibition of Herba Epimedii on Rat’s Model of Hypothalamus - pituitary -adrenal -thymus axis.[J]. Journal of Traditional Chinese Medicine1996, (10): 620-621.
Inhibition of Herba Epimedii on Rat’s Model of Hypothalamus - pituitary -adrenal -thymus axis.[J]. Journal of Traditional Chinese Medicine1996, (10): 620-621.DOI: 10.13288/j.11-2166/r.1996.10.026.
Rat models of HPAT inhibition were made by corticosterone for observation on the adjusting action of a Yang - stimulant. Herba Epimedii. Results included marked reduction in weights of rats pituitary
adrenal and thymus
the CRF positive cells from microcellular area of hypothalamic paraventricles
positive nerve fibres of CRF
positive cells of ATCH were also markedly reduced
with decreased cellular size
and light staining
marked decrease in the sizes of adrenals and thymus glands. There were also marked decrease of plasmal ACTH
cortisone
lymphocyte proliferative reaction
NKCC
7 - IFN induced growth capacity as compared with normal control group. Gastric infusion of Herba Epimedii effectively ameliorated the inhibition of HPAT morphorolgy and functions by cortisone
suggesting that this herb yields important action on neural and hormonal immunity.