Exporation on Improving Action of Nourishing -yin to Reduce Fire Herbals on Bone Growth in Children of Sexual Precocity and Its Mechanism[J]. Journal of Traditional Chinese Medicine1997, (10): 615-617.
Exporation on Improving Action of Nourishing -yin to Reduce Fire Herbals on Bone Growth in Children of Sexual Precocity and Its Mechanism[J]. Journal of Traditional Chinese Medicine1997, (10): 615-617.DOI: 10.13288/j.11-2166/r.1997.10.023.
with herbals of nourishing - yin to reduce fire combined with megestrol (Group A)
another 32 cases were treated with megestrol alone (Group B) for a course of 1 year. Twenty -five cases were untreated as control (Group C). Results showed: for Group C after 1 year
the value of BA/ CA increased from 1. 39 ± 0. 24 to 1. 54 ± 0. 2 (P<0. 01). The predicted final body height decreased from 154. 2 ± 5. 3 cm to 149. 4 ± 4.8cm
(P<0. 01). For Group B
no obvious effects were shown in both values. For Group A
the growth rate of the children slowed down BA/ CA decreased from 1. 36 ± 0. 19 to 0. 65 ± 0. 16 (P<0. 001) the final predicted body height increased from 153. 6 ±3. 8 cm to 158. 8 ± 4. 4 cm (P<0. 001)
demonstrating that the said herbals markedly slow down the growth of skeleton
delays its matirity. thus prevents the premature fusion of epiphysis and improves the final body height.Fifty cases of female idiopathic precocity were treated