活血化瘀强度与气血双亏型胃癌转移率相关性机理探讨

徐德成; 张培宇

doi:10.13288/j.11-2166/r.1998.03.019

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活血化瘀强度与气血双亏型胃癌转移率相关性机理探讨

更新时间：2021-11-20

- 活血化瘀强度与气血双亏型胃癌转移率相关性机理探讨
- Exploration on Correlative Mechanism Between Intensity of Blood - activation Stasis - removal and Metastasis of Stomach Carcinoma of Deficient Type of Both Qi and Blood
- 中医杂志 1998年第3期页码：156-157
- 作者机构：
  
  1. 中国铁道建筑总公司总医院
  2. 中国中医研究院广安门医院北京石景山区京原路5号院,100043
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.1998.03.019
  中图分类号： R273
- 纸质出版：1998
- 稿件说明：
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[1]徐德成,张培宇.活血化瘀强度与气血双亏型胃癌转移率相关性机理探讨[J].中医杂志,1998(03):156-157+132.

Exploration on Correlative Mechanism Between Intensity of Blood - activation Stasis - removal and Metastasis of Stomach Carcinoma of Deficient Type of Both Qi and Blood[J]. Journal of Traditional Chinese Medicine1998, (3): 156-157.
[1]徐德成,张培宇.活血化瘀强度与气血双亏型胃癌转移率相关性机理探讨[J].中医杂志,1998(03):156-157+132. DOI： 10.13288/j.11-2166/r.1998.03.019.

Exploration on Correlative Mechanism Between Intensity of Blood - activation Stasis - removal and Metastasis of Stomach Carcinoma of Deficient Type of Both Qi and Blood[J]. Journal of Traditional Chinese Medicine1998, (3): 156-157. DOI： 10.13288/j.11-2166/r.1998.03.019.

摘要

本文回顾研究了益气生血方剂中活血化瘀强度与气血双亏型胃癌转移率之间的相关性

显示两者有较强的正相关

提示气血双亏型胃癌转移率随活血化瘀作用加强而增高。推测可能与本型胃癌血小板数量及聚集性下降、血浆纤维蛋白含量低及凝血抑制、纤溶增强易于肿瘤转移有关

且大多数活血化瘀方药具有抑制血小板聚集

抗血凝和增加纤溶的现代药理机制。进而建议气血双亏型胃癌

在血小板数量及聚集率明显下降、凝血时间明显延长及FDP高时

尽量降低方剂中活血化瘀强度

以避免促进肿瘤转移。

Abstract

Retrospective study was made on the correlation between the intensity of blood - activation stasis -removal drugs in Yiqi Shengxue Recipe and the metastasis of qi - blood deficiency type of stomach carcinoma

with a positive result

demonstrating that the rat’s of its metastasis increased with the intensity of the drugs. It is suggested that this might be due to the decrease of platelet count and its aggregation

low plama fibrinogen . and increase of fibrinolysis in these patients. Moreover

medern pharmacology shows that most drug and recipes of blood - activation stasis -removal inhibit the platelet aggregation

blood coagulation

and increase fibrinolysis. It is suggested that

in such patients

when the pletelet count and their aggregation are markedly decreased

prolonged blood coagulation time with high FDP. the intensity of the drugs should be lowered so as to avoid metastasis.

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