By first infusing large dose cold nature drugs

followed by ligating the anterior descending branch of left coronary artery and gradually narrowing down their aortic calibre

animal models were made 7-9 days after the operation

manifesting lassitude

drowsy

withered hairs

cyanotic lips and auricles

dropsy of feet. The surface temperature difference of extremities and abdomen was expanded than that of the pseudooperated animals （P<0. 001）. It was found in the killed animals that the myocardium was necrotic at the ligated site with hypertrophy of other heart muscles

ecchymosis of liver tissue

the indices of heart body weight

liver and liver weight/body weight/were markedly elevated as compared with those of pseudo operated animals （P<0. 05）. The left intraventricular pressure was also higher （P<0. 01） the maximal increase velocity of its left ventricular pressure was also greatly increased （P<0. 05）. Thus

the animal model was succesfully established.