Fifty cases of nephrosis in children were treated by combined use of the methods of nourishing - yin -decreasing - fire

invigorating - Qi - benefiting -kidney

and activating -circulation -removing -stasis and hormone -immune depressor. The patients’ body height

exams of scondary sex characters were examined at the OPD and follow -up at home

and the age of their first appearance of seminal emission or menstruation

the bone - age measurement of left wrist bone by X - ray film and were compared with another 31 cases of children treated by the same remedy but without TCM theropies. The retardation of sexual development in the treatment group was greatly decreased.