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1. 湖南中医学院第二附属医院耳鼻喉科
2. 湖南中医学院第二附属医院耳鼻喉科 长沙市蔡锷北路185号,410005
纸质出版:1998
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[1]徐绍勤,谭敬书,曾省三,李凡成,彭斌.补肾药物对庆大霉素致豚鼠耳中毒的保护作用[J].中医杂志,1998(07):430-431+388.
Protective Action of Kidney - tonics on Oto - intoxication of Gentamycin in Guinea Pig[J]. Journal of Traditional Chinese Medicine1998, (7): 430-431.
[1]徐绍勤,谭敬书,曾省三,李凡成,彭斌.补肾药物对庆大霉素致豚鼠耳中毒的保护作用[J].中医杂志,1998(07):430-431+388. DOI: 10.13288/j.11-2166/r.1998.07.030.
Protective Action of Kidney - tonics on Oto - intoxication of Gentamycin in Guinea Pig[J]. Journal of Traditional Chinese Medicine1998, (7): 430-431. DOI: 10.13288/j.11-2166/r.1998.07.030.
给豚鼠每日肌注庆大霉素80mg/kg的同时
喂服补肾药物
共20日。采用测定用药前后听觉脑干诱发电位阈值
耳蜗铺片行毛细胞观察计数
耳蜗超微结构电镜观察等方法。结果证实
补肾药物可保护听毛细胞
有效拮抗庆大霉素所致之听阈升高。说明补肾药物可保护耳蜗结构及功能
减轻庆大霉素的耳毒性反应。
By adopting induction - electricity threshold of brain stem
counting of hairy cells in cochlear membrane
and electromicroscopic exam of ultra microscopic sturcture before and after the administration of the drug
it was shown that kidney tonics can protect the hairy cells
effectively resist the increased of hearing threshold caused by gentamycin
demonstrating that such kidney tonics can protect the cochlear structure and function
minimize the oto - toxicity of gentamycin.
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