The biochemical and other lab indices of blood in 35 cases of nephrosis syndrome （NS） treated with Huangqi Xianlingpi Decoction plus Hirudo （HQXL） were observed. The results that HQXL was capable of decreasing urine protein

increasing plasma protein

lowering blood lipids （P < 0. 05 oiP < 0. 01）; the whole blood viscosity

plasma viscosity

RBC rouleaux - formation index

and finbrinagen all markedly decreased

electrophoresis time of RBC shortened （P < 0. 01）; blood TXB2 lowered

6 -ketone - PG F1α elevated （P < 0. 01）. The clinical effected of HQXL was significantly superior to the control group

demonstrating that HQXL is capable of improving NS patient’s hyperprobinemia

ameliorating proteinurea and protecting kidney function.