Effect of Huanyuan Injection (HY) on the Metabolism of Lactic acid, Ca2+ and Free Radicals in Brain Tissue of Rats of Acute Cerebral Hemorrhage[J]. Journal of Traditional Chinese Medicine2000, (2): 106-107. DOI: 10.13288/j.11-2166/r.2000.02.030.
Effect of Huanyuan Injection (HY) on the Metabolism of Lactic acid, Ca2+ and Free Radicals in Brain Tissue of Rats of Acute Cerebral Hemorrhage[J]. Journal of Traditional Chinese Medicine2000, (2): 106-107. DOI: 10.13288/j.11-2166/r.2000.02.030.DOI:
Cerebral hemorrhage model of rat was prepared by injecting 0. 5μl collagenase saline into its internal capsule and observation performed on the effect of HY on the contents of lactic acid. Ca2+. SOD. MDA in the hematoma area in the brain. Qingkailing (QKL) injection was used as control. Results revealed that the contents of lactic acid Ca2+. MDA in the model control group were obviously higher than that of the normal and operated control groups (P < 0. 01)
activity of SOD markedly lowered than that the other 2 groups (P <. 0.01). The contents of lactic acid
Ca2+
MDA in the HY group were all obviously lowered than that of the model -control group (P < 0. 05 or P < 0. 01). activity of SOD markedly higher than that of the model - control group (P< 0. 05 or P<0. 01). The action of lowering the content of MDA of HY group was superior to the QKL control group (P < 0.05).