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1. 中国中医研究院基础理论研究所
2. 中国中医研究院医学动物实验中心
3. 中国中医研统院基础理论价究所
4. 中国药品生物制品检定所 北京市东直门内北新仓18号,100700
纸质出版:2001
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[1]陈小野,周永生,邹世洁,蒋小丽,樊雅莉,张宇鹏,崔成德,邵德彬,王丽芳,王肃,贺争鸣.10种雄性大鼠的中医体质学初步研究[J].中医杂志,2001(01):45-47+4.
Preliminary Study on TCM Crasiology in 10 Strains of Male Rats[J]. Journal of Traditional Chinese Medicine2001, (1): 45-47.
[1]陈小野,周永生,邹世洁,蒋小丽,樊雅莉,张宇鹏,崔成德,邵德彬,王丽芳,王肃,贺争鸣.10种雄性大鼠的中医体质学初步研究[J].中医杂志,2001(01):45-47+4. DOI: 10.13288/j.11-2166/r.2001.01.029.
Preliminary Study on TCM Crasiology in 10 Strains of Male Rats[J]. Journal of Traditional Chinese Medicine2001, (1): 45-47. DOI: 10.13288/j.11-2166/r.2001.01.029.
为了对10种北京市目前常用的雄性实验大鼠进行中医体质检测
用雄性大鼠
品系有WistarⅠ级、Ⅱ级、Ⅲ级
SDⅠ级、Ⅱ级、Ⅲ级
CD(SD)IGSⅢ级(大、小体重)
SHRⅠ级
SHR/spⅠ级。观测外观、大便、舌象、体温、肾上腺、胸腺、脾脏湿重
测定下丘脑—垂体—甲状腺轴相关功能。结果
WistarⅠ级、Ⅱ级、Ⅲ级
SDⅢ级大鼠体质基本正常
SDⅠ级大鼠略有虚热体质
SD Ⅱ级大鼠有实热体质
CD(SD)IGS Ⅲ级(小、大)大鼠略有虚性体质
SHRⅠ级大鼠略有虚寒体质
SHR/spⅠ级大鼠有明显虚寒体质
表明不同品系、同品系不同微生物等级、纯系与非纯系、不同年龄大鼠的中医体质比较有一定差异。
Ten strains of male rats are commonly used for experimental study at present in Beijing. The rats’ outward appearence
stool
picture of the tongue
body temperature
and wet weight of adrenal gland
thymus gland and spleen were observed
and the function of the hypothulamus pituitary thyroid axis was determined. Results showed that the constitution of Wistar grade Ⅰ
Ⅱ
Ⅲ
and SD grade Ⅲ were basically normal. SD grade Ⅰ had the constitution of mild deficiency - cold
SD grade Ⅱhad constitution of excess - heat
CD (SD) IGS grade Ⅲ (small or big body weight) had constitution of mild deficiency
SHR grade I had constitution of mild deficiency -cold
SHR/sp grade I had obvious deficiency -cold constitution; There was a certain difference in TCM constitution among different strains
same strain with differrenct microbic grades
pure line and inbred line
and different ages in rats. It is indicated that the study on TCM crasiology in experimental animals are not only necessity
and also feasibility.
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