Effects of Electroacupuncture on Learning and Memory Behaviour and Acetylcholinesterase of Brain in the rat of Vascular Dementia[J]. Journal of Traditional Chinese Medicine2001, (6): 344-346.
Effects of Electroacupuncture on Learning and Memory Behaviour and Acetylcholinesterase of Brain in the rat of Vascular Dementia[J]. Journal of Traditional Chinese Medicine2001, (6): 344-346.DOI: 10.13288/j.11-2166/r.2001.06.023.
Effects of electroacupuncture (EA) on learning and memory and acetylcholinesterase (AChE) activity were investigsted in the rat of vascular dementia. Thirty rats were randomly divided into model group
EA group and medicine (Dyhydroergotoxine
DHET) group
10 rats in each group. After treatment for 28 days
learning and memory behaviour were detected with water maze
and the AChE activity in brain was determined. Results showed that the latent period of water maze in the EA group and the medicine group was shorter than that of the model group (P < 0. 05 or P < 0. 01)
respectively
and in the EA group was shorter than in the medicine group (P<0. 05 or P< 0. 01). The AChE activities of hippocampus and striatum in the EA group and the medicine group were higher than those in the model group
and the EA group was higher than the medicine group (P<0. 05). It indicates that electroacupuncture can promote the ability of learning and memory and enhance AChE activity of brain in rats of vascular dementia
and the therapeutic effect of electroacupuncture is better than that of DHET.